Yang X

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common disorder affecting the reproductive, endocrine, and metabolic systems in women. Dysfunction of granulosa cells (GCs) and imbalance of the immune microenvironment are key pathological …

Bisphenol A (BPA), an endocrine-disrupting chemical frequently detected in follicular fluid (FF), has been implicated in ovarian reserve dysfunction. However, data on the presence of its structural analogues within ovarian follicles remain …

Accurate pre-operative discrimination between ovarian endometriomas (EMs) and other benign ovarian tumors is crucial for surgical planning and fertility counseling. This study aimed to evaluate the diagnostic performance of serum CA125, CA1…

BACKGROUND: Ovarian endometriotic cysts represent a prevalent form of endometriosis and are typically identifiable via imaging modalities. Nonetheless, differentiating endometriotic cysts from other benign non-endometriotic ovarian cysts, s…

OBJECTIVE: High-intensity focused ultrasound (HIFU) therapy is increasingly used in the management of various solid tumors. However, limited data are available regarding the association between HIFU treatment and coagulation function. MATE…

BackgroundThe relationship between preimplantation hematological profiles and clinical pregnancy rates following frozen embryo transfer (FET) has not been thoroughly investigated.MethodsA retrospective study was conducted. Participants were…

BACKGROUND: In recent years, microRNAs have attracted increasing attention for their potential diagnostic and prognostic value across various diseases. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of mi…

INTRODUCTION: Endometriosis (EM) is an inflammatory condition that affects approximately 10% of the female-born population. It is characterized by the presence of endometrial tissue outside the uterine cavity, leading to chronic pelvic pain…

PROBLEMS: To investigate the impact of anti-endometrial antibodies (EMAb) on pregnancy outcomes in infertile patients undergoing in vitro fertilization (IVF) and to assess the potential value of personalized treatment strategies. METHOD OF…

ObjectiveTo evaluate the impact of adjunctive levonorgestrel-releasing intrauterine device (LNG-IUD) placement on amenorrhea rates and hysterectomy risk following endometrial resection or ablation in women with abnormal uterine bleeding (AU…

BackgroundHeavy menstrual bleeding (HMB) is a common and debilitating condition in women with bleeding disorders (BD). The underlying hemostatic abnormalities in these patients often make standard treatments ineffective. Clinical management…

BACKGROUND: Endometriosis is a prevalent benign condition among women of reproductive age. While the overall rate of endometriosis-associated malignancy is low, the risk of malignant transformation increases significantly in postmenopausal …

BACKGROUND: Age-related diminished ovarian reserve (DOR) exhibits marked significant individual variation. Some women of advanced age with normal ovarian reserve (NOR) achieve better reproductive outcomes than age-matched DOR patients. OBJE…

BACKGROUND: Endometrial receptivity (ER) serves as a critical determinant for successful embryo implantation, yet its molecular complexity and limited clinical assessment methods pose significant challenges. Despite advancements in assisted…

This narrative review synthesizes the latest advances in nano-diagnostic and therapeutic reagents for acute pancreatitis (AP), based on peer-reviewed experimental and preclinical studies published in recent years. AP endangers life through …

RationaleHysterosalpingo-contrast sonography (HyCoSy) is a commonly used technique for assessing fallopian tube patency. A well-recognized complication of this procedure is venous intravasation (VI), which refers to the unintended entry of …

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese Medicine (TCM) offers multiple advantages in the treatment of endometriosis (EMS). Bushen Wenyang Huayu Decoction (BWHD) is widely used in clinical practice for managing EMS. It can signif…

BACKGROUND: LY01021 is a novel oral small-molecule gonadotropin-releasing hormone (GnRH) receptor antagonist intended for the treatment of various sex hormone-dependent disorders. This study aimed to evaluate the safety, tolerability, pharm…

BackgroundCompared with overnight insemination, it remains uncertain whether short-term insemination can improve outcomes in poor responders, and few studies have used cumulative live birth rate as the primary endpoint. The study aims to co…

BackgroundOvarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management re…

Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persisten…

The study explored the mechanism of Dan'e-fukang soft extract in treating endometriosis (EMs) through network pharmacology. The main active ingredients of Dan'e-fukang soft extract were analyzed based on the traditional Chinese medicine sys…

BackgroundUnexplained recurrent spontaneous abortion (URSA) poses a significant clinical challenge with an elusive pathogenesis. FABP4 is crucial for lipid homeostasis and placental development, but its specific role and regulatory mechanis…

BACKGROUND: Endometriosis, a common chronic gynecological disorder, involves cellular autophagy and inflammatory processes in its pathogenesis. However, the specific regulatory mechanisms of autophagy and inflammation in endometriosis remai…

ObjectiveTo investigate the effect of Tiao-Jing-Cu-Yun Acupuncture on pregnancy outcomes in infertility patients with thin endometrium undergoing artificial cycle frozen-thawed embryo transfer (AC-FET).MethodsA prospective, assessor-blinded…