Yoko Aoyagi
No ORCID on file
· 23 papers in corpus
· active 2013-2026
Study types
- article 17
- review 3
- other 2
- case-report 1
Condition tags
- endometriosis 17
- mesh:D004715 14
- endometrioma 2
- adenomyosis 1
Top journals
Frequent coauthors
- Kaei Nasu 22
- Hisashi Narahara 16
- Kentaro Kai 15
- Mamiko Okamoto 12
- Tomoko Hirakawa 12
- Kanetoshi Takebayashi 7
- Yuichiro Kawano 7
- Ruofei Zhu 5
- Wakana Abe 5
- Saki Aso 4
article
2026
other
2026
AIM: To investigate the mechanisms of histone deacetylase (HDAC) 10 inhibitors (HDAC10Is) action in endometriosis and the target molecules of HDAC10Is. METHODS: We assessed the effects of HDAC10Is, tucidinostat and TH34, on the proliferati…
article
2025
Objective: The microRNA hsa-miR-132-5p is upregulated in endometriotic cyst stromal cells (ECSCs). We investigate how hsa-miR-132-5p affects the progression of endometriosis. Methods: Normal endometrial stromal cells (NESCs) that have been …
case-report
2023
Both ovarian pregnancy and endometrioma can rupture and cause life-threatening hemoperitoneum. However, little is known about their coexistence. We report the case of a 34-year-old Japanese woman with a life-threatening hemoperitoneum in th…
other
2021
It is suggested that aberrantly expressed microRNAs are involved in the pathogenesis of endometriosis. Our previous study demonstrated that expression of the microRNA hsa-miR-199a-3p is attenuated in human endometriotic cyst stromal cells (…
review
2021
review
2021
article
2020
article
2020
BACKGROUND: A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stromal cells (ECSCs). …
article
2019
A number of genes involved in the pathogenesis of endometriosis are silenced by the hypermethylation of their promoter regions. We assessed the effect and mechanism of the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC) (10 μM) on…
article
2018
Background: The heritable silencing of genes, without a change in their coding sequence, is due to epigenetic mechanisms. These mechanisms involve DNA methylation, the modification of histone, and non-coding RNA. Disrupting the balance of t…
article
2017
BACKGROUND: We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to evaluate the potentia…
article
2017
article
2016
article
2016
article
2016
STUDY QUESTION: Is the micro-RNA (miRNA) miR-503, downregulated in endometriotic cyst stromal cells (ECSCs) and does this affect the cell cycle, cell proliferation, angiogenesis and contractility of these cells? SUMMARY ANSWER: miR-503 expr…
article
2015
article
2015
review
2014
Accumulating evidence suggests that epigenetic aberrations play definite roles in the pathogenesis of endometriosis. These include aberrations in genomic DNA methylation, microRNA expression, and histone modification. The aberrant histone m…
article
2014
article
2014
STUDY QUESTION: What are the roles of the microRNA miR-210-an miRNA that is up-regulated in endometriotic cyst stromal cells (ECSCs)-in the pathogenesis of endometriosis? SUMMARY ANSWER: Up-regulated miR-210 expression in ECSCs is involved …
article
2014
BACKGROUND: Glycosylation is one of the most common post-translational modifications of eukaryotic proteins and is known to undergo dynamic changes in a wide range of biological processes. To date, however, the glycan expression profiles in…
article
2013
PROBLEM: The purpose of this study is to evaluate the involvement of death receptor (DR) 6 in the pathogenesis of endometriosis. METHODS OF STUDY: Endometriotic cyst stromal cells (ECSCs) and normal endometrial stromal cells (NESCs) were is…