Hakan Aytan

Amaç: Bu çalışma, benign over kistleri için kistektomi yapılan hastalarda endometrioma için öngörücü bir biyobelirteç olarak immatür granülosit yüzdesi potansiyelini araştırmayı amaçlamaktadır. Yöntem: Bu retrospektif çalışma, Mersin Üniver…

Endometriosis and migraine are common chronic conditions in women of reproductive age that impair quality of life and frequently co-occur as comorbid conditions. Evidence regarding the effects of treatments targeting one of these conditions…

OBJECTIVE: To examine the correlation between levels of anti-Müllerian hormone (AMH)-which serves as an indicator of ovarian reserve-and inflammation markers in women with endometriomas. METHODS: This retrospective investigation involved 9…

Background and Objectives: The relationship between preoperative inflammatory markers and lymphovascular space invasion (LVSI) in endometrioid-type endometrial cancer (EC) remains incompletely defined and warrants evaluation using robust st…

Abstract Background This study sought to examine the function of hematological inflammatory markers in differentiating endometrioma from other benign ovarian cysts prior to surgery and in individuals with Douglas involvement. Materials and…

BACKGROUND: The coexistence of adenomyosis and cancer of the endometrium has attracted heightened scrutiny, leading to inquiries regarding their possible interactions and clinical ramifications. This study sought to assess the influence of …

Aim: This study aims to investigate the potential of immature granulocyte percentage as a predictive biomarker for endometrioma in patients undergoing cystectomy for benign ovarian cysts. Methods: This retrospective study was conducted at t…

Abstract Objectives Adenomyosis is a benign uterine disease that occurs with the invasion of the endometrial gland and stoma into the myometrium. The etiology and molecular pathology of adenomyosis are not yet fully understood. Tissue sampl…

OBJECTIVE: Adenomyosis is a benign uterine illness characterized by endometrial gland and stromal invasion into the myometrium. Acetyl-CoA acetyltransferase 1 (ACAT1) is an enzyme localized in mitochondria that is involved in ketogenesis an…

OBJECTIVE: To develop a scoring system using clinical evaluation methods to predict the presence of adenomyosis. MATERIALS AND METHODS: A cohort of 232 patients who underwent hysterectomy for benign gynecologic disorders was prospectively …

To assess the potential therapeutic role of antilipidemic ezetimibe on endometriosis in an experimental rat model. A standard experimental endometriosis model was created with 18 Whistar-Albino rats, and after 1 month, the sizes of the endo…

PurposeAdenomyosis is a benign uterine disease resulting from the myometrial invasion of the endometrial gland and stroma. In the current study, angiogenesis, apoptosis and energy metabolism were investigated in adenomyosis.MethodsA retrosp…

UNLABELLED: To assess the effects of the natural progesterone on the endometriosis in a rat model. MATERIALS AND METHODS: Endometriosis was surgically induced in 20 rats by transplanting an autologous fragment of endometrial tissue onto the…

Endometriosis is the presence of functional endometrial glands and stroma outside the uterine cavity. The abdominal wall is an uncommon site of extrapelvic endometriosis, where it usually develops in an old surgical scar. Common presentatio…

BACKGROUND: The effect of rosiglitazone, an activator of peroxisome proliferator-activated receptor-gamma, on the growth of ectopic uterine tissue was assessed. METHODS: Endometriosis was surgically induced in 28 rats by transplanting an au…

The effect of immunomodulator leflunomide on the development of an experimental endometriosis model was assessed by surgically transplanting autologous fragments of endometrial tissue onto the inner surface of the abdominal wall and arteria…

ObjectiveTo test if leflunomide, an immunomodulator, could impede the growth of an ectopic uterine tissue.MethodsEndometriosis was surgically induced in 26 rats by transplanting an autologous fragment of endometrial tissue onto the inner su…

ObjectiveTo assess the effect of the peroxisome proliferator-activated receptor (PPAR)-gamma agonist rosiglitazone on the induction of endometriosis in a rat model.MethodsEndometriosis was surgically induced in 28 rats by transplanting an a…