Zhou J

OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is primarily characterized by neonatal jaundice and acute/chronic hemolytic anemia. This study aimed to examine the influence of different G6PD genotypes on pregnancy and neonat…

BackgroundThe relationship between gonadotropin-releasing hormone agonists (GnRH-as) and depression and suicide/self-injury (DASSI) remains controversial. This study aimed to investigate this potential association using data from the FDA Ad…

Background: Ovarian endometriomas damage the ovarian structure, alter ovarian inflammation, and impair ovarian reserve. Given the conflicting results, determining an optimal reproductive strategy for women with endometriomas-whether expecta…

Yifei Sun,1– 7,* Zijing Wang,1– 7,* Jiayi Zhou,1– 7 Linlin Cui,1– 8 Huidan Wang1– 7 1State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive…

Endometriosis is a prevalent gynecological disorder associated with chronic low-grade inflammation, yet diagnosis is often delayed because symptoms are non-specific and definitive confirmation typically relies on invasive procedures. Compos…

BackgroundThis study aimed to evaluate the efficacy of growth hormone (GH) as an adjuvant treatment for enhancing embryo quantity in patients with poor ovarian response (POR) who previously had no viable embryos in in vitro fertilization (I…

BACKGROUND: Euploid miscarriage may indicate underlying non-genetic factors in the couples. This study aimed to investigate the subsequent live birth rates in women with a prior euploid or aneuploid sporadic miscarriage (SM) in assisted rep…

BACKGROUND: Studies have shown that dysregulation of the gut microbiota (GM) plays a crucial role in the development of endometriosis (EMs). Study aimed to investigate the potential of protective GM metabolites in treating EM through networ…

ObjectivesTo explore the correlation between different delivery methods for high-positioned fetal heads during cesarean section(CS) and obstetric complications.MethodsA retrospective analysis of 236 cephalic-position CS patients with high-f…

BACKGROUND: Endometrial cancer (EC) is one of the most common malignant tumors in women, and in recent years, the role of gut microbiota in tumorigenesis has gradually gained attention. Previous studies have shown that the gut microbiome is…

ObjectivesThis study aimed to develop a multimodal predictive model that integrates clinical data, radiomics, and three-dimensional deep learning to forecast acute respiratory distress syndrome in patients with acute pancreatitis.MethodsThi…

Diabetic kidney disease (DKD) is a prevalent complication in individuals with diabetes. Efferocytosis plays a pivotal role in chronic diseases; however, the precise mechanisms involved in DKD are still not fully understood. DKD-related data…

OBJECTIVES: Parthenolide (PTL) has significant anti-inflammatory and immunomodulatory effects, but its regulatory mechanisms in endometriosis (EMs) remain unclear. This study aimed to systematically evaluate the effects of PTL on cellular m…

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

Perfluorooctanoic acid (PFOA) has been implicated in female reproductive toxicity, while its long-term effects of prenatal exposure remain unclear. Herein, we conducted a comprehensive NHANES analysis to estimate the Hazard Ratio (HR) of ea…

Monkeypox virus (MPXV) infection-associated intestinal manifestations, including diarrhea and proctitis, have been frequently reported during mpox outbreaks. Here, we present clinical evidence that MPXV can directly infect the human intesti…

BACKGROUND: Pro-EGCG has shown therapeutic promise for endometriosis, yet its immunoregulatory mechanisms remain unclear. Myeloid-derived suppressor cells (MDSCs) are key drivers of disease progression. This study investigates whether Pro-E…

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully unde…

BackgroundImplantation failure is the most common cause of pregnancy failure and is a major limiting factor in assisted reproduction. Plasma microRNA (miRNA) expression profiles show dynamic changes among individuals with successful implant…

BackgroundUnexplained recurrent implantation failure (URIF) represents a complex and challenging condition in reproductive medicine, while the role of non-criteria antiphospholipid syndrome antibodies in its pathogenesis remains unclear. As…

Endometriosis (EMs) is an estrogen-dependent inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity, yet its precise pathogenesis remains incompletely elucidated. TICAM1, a key adaptor prote…

ObjectiveOur study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs).MethodsThe study population was sourced from two independent …

BACKGROUND: Ultrasound-guided anhydrous ethanol sclerotherapy (UGAES) is an effective treatment option for ovarian endometrioma-related pain and infertility. However, its use is limited by the fact that alcohol can sometimes cause unbearabl…

The JAK-STAT signaling pathway serves as a central regulator of diverse cellular processes encompassing proliferation, apoptosis, inflammation, and differentiation. Specifically, extracellular ligands such as interleukins, and colony-stimul…