Endometriosis is a puzzling and debilitating disease that affects millions of women around the world. Ovary is the most common organ site involved by endometriosis. Despite various hypotheses about its cell of origin, uncertainty remains. O…
OBJECTIVE: Human epididymis protein 4 (HE4) has been approved for diagnosing ovarian cancer. The goal of this meta-analysis was to evaluate the clinical value of the serum HE4 in the diagnosis of ovarian cancer. METHODS: The PubMed and Emb…
OBJECTIVES: To evaluate the clinical outcomes of gonadotropin-releasing hormone analog (GnRHa) combined with implantation of a levonorgestrel-releasing intrauterine system (LNG-IUS) in adenomyosis patients with significantly enlarged uterus…
Objective: To discuss the value of MR-hysterosalpingography(HSG) in diagnosing the tubal patency.Methods: A total of 20 infertile women were referred to conventional pelvic scanning by MRI and MR-HSG,and all subjects underwent conventional …
OBJECTIVE: To investigate the effects on pelvic pseudocyst, ovarian function and symptoms of peri-menopausal period in patients with benign uterine disease undergoing simultaneous hysterectomy and bilateral salpingectomy. METHODS: From Jan…
OBJECTIVE: To discuss the value of magnetic resonance hysterosalpingography (MR HSG) in diagnosing tubal patency of the fallopian tube. STUDY DESIGN: Conventional pelvic magnetic resonance imaging (MRI) and MR HSG were performed on 20 infe…
A lack of sensitive and specific tumor markers for early diagnosis and treatment is a major cause for the high mortality rate of ovarian cancer. The purpose of this study was to identify potential proteomics-based biomarkers useful for the …
BACKGROUND: To determine the effect of higher progesterone (P) level on endometrial receptivity. METHODS: This was a prospective analysis conducted in the Reproductive Medical Center of Peking University Third Hospital. All patients receiv…
OBJECTIVE: To evaluate the effects of tumor necrosis factor-alpha (TNF-alpha) on porcine oocyte maturation, spindle dynamics, and chromosome alignment. DESIGN: Controlled, prospective study. SETTING: University hospital and IVF research l…
Objective:To explore the impact of Juan tong Decoction over the serum and peritoneal fluid sICAM-1 of Endometriosis rat and the ICAM-1 expression of Ectopic endometrial lesions. Methods:The SPF level of female SD rats were randomly divided …
OBJECTIVE: To evaluate long term effect and related factors in patients with menorrhagia treated by microwave endometrial ablation (MEA). METHODS: Total of 334 women with menorrhagia were treated by MEA, the range of age was from 29 to 59 …
Objective:To investigate the long-term effects and safety of combinative treatment with laparoscopy and gestrinone on ovarian endometriosis.Methods:108 cases diagnosed ovarian endometriosis were divided into two groups:the study group(n=58)…
Objective:To observe the expression of matrix metalloproteinase-7(MMP-7) and tissue inhibitors of matrix metalloproteinase-1(TIMP-1) in endmetriosis.and to study the possible role of MMP-7 and TIMP-1 in the pathogenesis of endmetriosis.Meth…
Objective:To explore the effect of insulin-like growth factor Ⅱ(IGF-Ⅱ) and its receptor(insulin-like growth factor Ⅱ receptor,IGF-ⅡR) in the development of ovarian endometriosis.Methods: 24 patients underwent hysterectomy and adnexectomy fr…
目的观察基质金属蛋白酶-7(matrix metalloproteinase-7,MMP-7)和基质金属蛋白酶抑制因子-1(tissueinhibitors of matrix metalloproteinase-1,TIMP-1)在子宫内膜异位症(Endmetriosis,EMs)中的表达,探讨二者在EMs发病机制中的作用。方法采用免疫组化链霉菌抗生物素蛋白-过氧化物酶连接(SP)法检测35例EMs患者的在位内膜,异位内膜及20例对照组为因肌壁间或浆膜下子宫肌瘤在我科行子宫…
OBJECTIVE: To investigate the impact of danazol alginate microspheres used for uterine arterial embolization (UAE) on ovarian function and subsequent pregnancy using rabbit as a model. METHODS: A total of 32 female rabbits were divided int…
Objective To explore the relations between the expression of CD44v6 and laminin and endometriosis. Methods Expression of CD44v6 and laminin were evaluated by immunohistochemistry in entopic endometrium from 22 patients and in ectopic endome…
Objectives:To study the value of high-frequency ultrasonic and CDFI for the diagnosis of the endometriosis in the scar abdominal wall after caesarean section.Methods:26 patients who had been authenticated with the endometriosis in the scar …
Objective To analyze the MRI and DSA feature of uterine adenomyosis, and further understand its imaging apperance. Methods MR imaging and DSA were performed in 27 cases of uterine adenomyosis before TUAE. MR imaging consisted of T1-weighted…
Objective To investigate the proper meth od and power of unipolar electrocoagulation in treatment of endometriosis. Methods Endometriosis was induced in 40 mature female rats by transplantation of endometrium on the peritoneum. Five weeks l…
Objective To investigate the relationship between E-cadherin(E-cad),α-catenin(α-cat) and endometriosis(EM). Methods Expression of E-cad and α-cat was evalutated by immunohistochemistry method in eutopic and ectopic endometrial tissues from …
Objective To explore the immune mechanism of endometriosis induced infertility.Methods The infertile women with mild endometriosis were chosen and those with polycystic ovarian syndrome and unidentified causes as controls. The levels of IL …
Objectives:To discuss the value of laparoscopic Semm's hysterectomy in gyneologic field.Methods:Retrospective analysis the conditions of the operation of the 72 patients undergoing laparoscopic Semm's hysterectomy(N1 group) and 35 patients(…