Clinical Observation of Combinative Treatment on Ovarian Endometriosis with Laparoscopy and Gestrinone——108 Cases

Objective:To investigate the long-term effects and safety of combinative treatment with laparoscopy and gestrinone on ovarian endometriosis.Methods:108 cases diagnosed ovarian endometriosis were divided into two groups:the study group(n=58)and the control group(n=50)by laparoscopy during August,2003 to December,2004.The patients in study group were given 2.5 mg of gestrinone twice a week for 3~6 months after operation.The cases in control group had not taken any hormone.All patients were fol- lowed up 6 months to 3 years to observe curative effect,and 1 of them lost.Results:All patients were successfully treated by laparoscopic operation,and the follow-up rate was 99.08 %.The total effective rate had statistical significance between the study group(86.21%)and the control group(64.00 %)(P0.01).The recurrence rate of study group was 10.34 %,which was significantly lower than that of control group(31.25%)(P0.01).18 of 34 cases with infertility and pregnancy request had pregnancy.Conchusion:Gestrinone is a safe and ef- fective therapeutic means for ovarian endometriosis,which can significantly decrease the recurrence rate and increase the pregnancy rate.