Ayako Watanabe

No ORCID on file · 7 papers in corpus · active 1996-2009

Study types

  • article 7

Condition tags

  • endometriosis 5
article 2009
ORIGINAL ARTICLE: TNFα Gene Silencing Reduced Lipopolysaccharide‐Promoted Proliferation of Endometriotic Stromal Cells
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2009.00691.x

PROBLEM: We previously reported that lipopolysaccharide (LPS)-promoted endometriotic stromal cell (ESC) proliferation by inducing TNFalpha production. The aim of this study was to investigate the efficacy of TNFalpha gene silencing on LPS-t…

article 2009
TAK1 activation for cytokine synthesis and proliferation of endometriotic cells
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2009.04.012

Endometriosis causes pelvic pain and infertility in women of reproductive age. We explored TNFalpha-induced specific signaling pathways and gene expressions in endometriotic stromal cells (ESCs). Based on the data of the pathway specific cD…

article 2009
The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis
Human Reproduction ·doi:10.1093/humrep/dep305

BACKGROUND: Decreased susceptibility of endometrial tissue to apoptosis may contribute to the pathogenesis of endometriosis. We investigate the role of survivin in the pathophysiology of endometriosis through the ability of ectopic and euto…

article 2008
Exploring mechanisms for regulating growth and survival of ectopic endometriotic cells using comprehensive DNA microarray analysis
·doi:10.1016/j.fertnstert.2008.07.236
article 2008
Interleukin-10 attenuates TNF-α–induced interleukin-6 production in endometriotic stromal cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.04.052

ObjectiveTo determine whether high levels of interleukin (IL)-10 can attenuate the production of tumor necrosis factor (TNF)-alpha-induced proinflammatory cytokines in endometriotic stromal cells.DesignProspective study.SettingDepartment of…

article 2007
Apoptosis and endometriosis
Frontiers in bioscience : a journal and virtual library ·doi:10.2741/2302

Apoptosis plays a critical role in maintaining tissue homeostasis and represents a normal function to eliminate excess or dysfunctional cells. Accumulated evidence suggest that apoptosis helps to maintain cellular homeostasis during the men…

article 1996
Anin VitroSystem for Identifying Agents Capable of Changing Serum Lipoprotein(a) Concentration by Regulating the Transcriptional Activity of the Apolipoprotein(a) Gene Promoter
·doi:10.1006/bbrc.1996.1547

A high serum concentration of lipoprotein(a) [Lp(a)] is a significant and independent risk factor for cardiovascular disease. We examined the effects of agents on the transcriptional activity of the apolipoprotein(a) [apo(a)] gene promoter …