Hideo Honjo

No ORCID on file · 23 papers in corpus · active 1989-2007

Study types

  • article 19
  • other 2
  • review 2

Condition tags

  • mesh:D004715 20
  • endometriosis 20
  • adenomyosis 10
  • infertility 1
  • mesh:D017699 1
  • mesh:D004412 1
article 2007
Association of Killer Cell Immunoglobulin‐like Receptor Genotypes with Susceptibility to Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2007.00533.x

PROBLEM: Endometriosis is an immune-related chronic inflammatory disease with a polygenic predisposition. The aim of this study was to investigate whether polymorphisms in killer cell immunoglobulin-like receptors (KIRs) is responsible, in …

article 2007
Maintenance therapy involving a tapering dose of danazol or mid/low doses of oral contraceptive after gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.052
article 2006
Association of Two Polymorphisms in the Peroxisome Proliferator-Acativated Receptor-γ Gene With Adenomyosis, Endometriosis, and Leiomyomata in Japanese Women
Journal of the Society for Gynecologic Investigation ·doi:10.1016/j.jsgi.2006.03.005
article 2006
Synergistic effect of interleukin‐6 promoter (IL6 −634C/G) and intercellular adhesion molecule‐1 (ICAM‐1 469K/E) gene polymorphisms on the risk of endometriosis in Japanese women
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2006.00426.x

PROBLEM: Endometriosis is an immune-related, chronic inflammatory disease with a polygenic predisposition. The aim of this study was to investigate whether the interleukin-6 (IL-6) gene promoter region polymorphism (-634C/G) and the interce…

article 2005
Expression of Allograft Inflammatory Factor-1 in Human Eutopic Endometrium and Endometriosis: Possible Association with Progression of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2004-0871

Allograft inflammatory factor-1 (AIF-1) is a cytokine originally identified in rat cardiac allografts with chronic rejection. AIF-1 is expressed in various human immune-related tissues and is thought to play a role in inflammatory responses…

article 2005
Usefulness and limits of CA-125 in diagnosis of endometriosis without associated ovarian endometriomas
Human Reproduction ·doi:10.1093/humrep/deh890

BACKGROUND: The aim of this study was to evaluate the diagnostic significance of CA-125 for endometriosis without ovarian endometriomas. METHODS: Preoperative serum CA-125 levels were measured in 775 consecutive women diagnosed by laparosco…

other 2004
Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2004.00168.x

PROBLEM: Tumor necrosis factor (TNF)-alpha is a major cytokine involved in inflammatory and immune function. The aim of this study was to investigate whether polymorphisms at positions -1031, -863 and -857 in the TNF gene promoter region (T…

article 2004
Interferon-  gene dinucleotide (CA) repeat and interleukin-4 promoter region (-590C/T) polymorphisms in Japanese patients with endometriosis
Human Reproduction ·doi:10.1093/humrep/deh337

BACKGROUND: Endometriosis is a multifactorial disease with possible genetic predisposition and involvement of environmental factors in its pathogenesis. Cytokines may play important roles in the pathogenesis of endometriosis. The aim of thi…

article 2003
Gonadotropin-releasing hormone agonist and danazol normalize aromatase cytochrome P450 expression in eutopic endometrium from women with endometriosis, adenomyosis, or leiomyomas
Fertility and Sterility ·doi:10.1016/s0015-0282(02)04813-6
article 2002
Association of HLA class I and class II alleles with susceptibility to endometriosis
Human immunology ·doi:10.1016/s0198-8859(02)00438-x
article 2002
Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women
Human Reproduction ·doi:10.1093/humrep/17.4.897

BACKGROUND: To investigate whether polymorphisms of CYP17 and CYP19 genes are associated with the risk of endometriosis, we analysed the frequency and distribution of a single nucleotide polymorphism at the 5' untranslated region of the CYP…

review 2002
Endometriosis: the pathophysiology as an estrogen-dependent disease
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/s0960-0760(02)00260-1
other 2002
Genetic contribution of the interleukin-10 promoter polymorphism in endometriosis susceptibility
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2002.1o029.x

PROBLEM: Interleukin-10 (IL-10) is an important immunomodulatory cytokine. The aim of this study was to investigate whether polymorphisms of the IL-10 gene promoter polymorphisms may be responsible in part for genetic susceptibility to endo…

article 2001
[Hormone responsiveness of endometriosis].
Nihon rinsho. Japanese journal of clinical medicine
article 2001
Immunohistochemical localization of aromatase and apoptosis-associated proteins in ovarian serous cystadenocarcinoma arising from ovarian endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/s0301-2115(01)00288-3
article 2000
Progesterone Induction of 17β-Hydroxysteroid Dehydrogenase Type 2 during the Secretory Phase Occurs in the Endometrium of Estrogen-Dependent Benign Diseases But Not in Normal Endometrium
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.9.6829

In the human endometrium, inactivation of 17beta-estradiol to estrone is catalyzed by 17beta-hydroxysteroid dehydrogenase type 2 (17betaHSD2). Previous studies have shown that the 17betaHSD2 activity in the endometrium is elevated during th…

article 1999
Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00424-0
review 1999
Expression of Aromatase Cytochrome P450 in Eutopic Endometrium and Its Application as a Diagnostic Test for Endometriosis
Gynecologic and obstetric investigation ·doi:10.1159/000052865

Endometriotic implants, like other estrogen-dependent tumors, contain both estrogen receptors and aromatase cytochrome P450 (P450arom), suggesting that at a local level, endometriotic implants produce estrogens, which may be involved in tis…

article 1998
Expression of exon 5 deleted estrogen receptor variant messenger RNA in human uterine myometrium and leiomyoma
·doi:10.1016/s0960-0760(98)00072-7
article 1997
Expression of Aromatase Cytochrome P450 Protein and Messenger Ribonucleic Acid in Human Endometriotic and Adenomyotic Tissues but not in Normal Endometrium1
Biology of reproduction ·doi:10.1095/biolreprod57.3.514

To determine whether local estrogen production takes place in endometriotic or adenomyotic tissues, in eutopic endometrium from patients with endometriosis or adenomyosis, and in normal endometrium, tissue specimens were examined by immunoh…

article 1997
Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium. Biol. Reprod

To determine whether local estrogen production takes place in endometriotic or adenomyotic tissues, in eutopic endometri-um from patients with endometriosis or adenomyosis, and in normal endometrium, tissue specimens were examined by im-mun…

article 1991
Drug delivery of hydroxypropylcellulosum jelly for drug delivery of danazol in rats and rabbits
article 1989
Estrogen biosynthesis in human uterine adenomyosis
Acta endocrinologica ·doi:10.1530/acta.0.1210259

Estrogen biosynthesis (aromatase activity) was investigated in human adenomyosis tissue and compared with that of the normal myometrium, endometrium, and endometrial cancer tissues. Homogenates were incubated with [1,2,6,7-3H]androstenedion…