Robert N. Taylor
ORCID: 0000-0002-1423-6351
· 131 papers in corpus
review
2002
OBJECTIVE: Rapidly evolving methods in genomics and proteomics research already are changing the nature of biomedical investigation. In this report we briefly review some of the seminal technological advances that inspired the genomics revo…
2002
2002
lab-animal
2002
RANTES (regulated on activation, normal T cell expressed and secreted) is synthesized by endometrial and endometriotic stromal cells and circulates in peritoneal fluid. Reports indicate that medroxyprogesterone acetate (MPA) is clinically e…
2002
2002
lab-animal
2002
An important step in the monthly turnover of the endometrial lining during the menstrual cycle is the cyclical recruitment and activation of inflammatory cells. Regulated Upon Activation Normal T Cell Expressed and Secreted (RANTES) has bee…
lab-animal
2002
Die Migration von Makrophagen in die Peritonealhöhle ist ein wesentlicher pathophysiologischer Faktor der Endometriose. Frühere Daten aus unserem Labor deuteten darauf hin, dass RANTES (Regulated on Activation, Normal T cell Expressed and S…
2001
Endometriosis is a common gynecologic disorder defined by the presence, growth, and progression of endometrial tissue outside the uterine cavity. Endometriosis can be asymptomatic, but it typically is associated with a multitude of clinical…
2001
lab-animal
2001
The human endometrium is a complex tissue comprised of different cell types, including epithelial, stromal, inflammatory, perivascular, and blood vessel cells. The hormonal receptivity and distribution of these cell populations change durin…
other
2001
OBJECTIVE: The immunological mechanisms that support persistence and proliferation of ectopic endometrial implants within the peritoneal cavity of women with endometriosis are unknown. Inhibition of natural killer (NK) and cytotoxic T-cell …
review
2001
OBJECTIVE: To provide a review of the humoral and cellular immunology of endometriosis and to discuss the rationale for future approaches to diagnosis and treatment. DESIGN: Literature survey. RESULT(S): Defective immunosurveillance in wo…
lab-animal
2001
The peroxisome proliferator-activated receptors (PPARs) alpha and gamma are nuclear receptors that play important roles in inflammatory diseases like ulcerative colitis and arthritis. In this study, we examined the possible role of PPARs in…
lab-animal
2001
Chemoattraction of macrophages and T cells into the normal endometrium and inflammatory sites within endometriotic foci is mediated by chemokine gene expression. mRNA transcripts encoding regulated on activation, normal T-cell-expressed and…
review
2000
Endometriose ist ein komplexes Krankheitsbild, dessen Pathogenese rätselhaft ist. Praktisch mit jedem Zyklus gelangen Endometriosezellen durch retrograde Menstruation in die Abdominalhöhle. Ein Ansiedeln dieser Zellen in ektopem Gewebe komm…
2000
2000
lab-animal
2000
Activated peritoneal macrophages are associated with endometriosis and may play a central role in its aetiology by releasing interleukin-1beta (IL-1beta) in response to refluxed endometrium. Pari passu with the establishment of endometrioti…
other
2000
Our laboratories have focused recently on the production and localization of eotaxin, a C-C-chemokine of 8.4 kDa, whose major biological activity is the chemoattraction of eosinophils. Given evidence of autoimmune activity in the endometrio…
other
2000
A key mechanism underlying the cyclical growth of the endometrium is its ability to regenerate a vascular capillary network. In normal cycling human endometrium, angiogenesis is influenced by both endocrine and paracrine factors. Hormonal m…
review
1999
Endometriosis is a common gynecological disorder with varied symptomatology including chronic pelvic pain, dysmenorrhea, and infertility. The association of endometriosis and infertility has been recognized for years, although definite evid…
review
1997
Recent studies suggest that the symptoms associated with endometriosis are the result of local peritoneal inflammation. Increased concentrations of activated pelvic macrophages and lymphocytes and the elevated levels of specific cytokines a…
review
1997
Endometriosis is a common gynecological disorder with varied symptomatology including chronic pelvic pain, dysmenorrhea, and infertility. The association of endometriosis and infertility has been recognized for years, although definite evid…
lab-animal
1997
Retrograde menstruation is postulated as the initiating event in the histogenesis of endometriosis; however, subsequent steps in the pathogenesis of this common disorder remain poorly characterized. The ip accumulation of activated leukocyt…