Hubbard GB

We present the spontaneous pathological lesions identified as a result of necropsy or biopsy for 245 chimpanzees (Pan troglodytes) over a 35-year period. A review of the pathology database was performed for all diagnoses on chimpanzees from…

BackgroundWe report the causes of mortality for 4350 captive baboons that died or were euthanized due to natural causes during a 23 year period at the Southwest National Primate Research Center.MethodsNecropsy records were retrieved and rev…

BackgroundBaboons are useful animal models for biomedical research, but the natural pathology of the baboon is not as well defined as other non-human primates.MethodsA computer search for all morphologic diagnoses from baboon necropsies at …

BACKGROUND: Endometrial and cervical polyps are masses of endometrium or cervical epithelium that bulge into the uterine or cervical lumen. The physiopathology and contributing factors of endometrial polyps development are still unknown. ME…

BackgroundGastrointestinal stromal tumors (GISTs) are believed to originate from the intestinal pacemaker cells (interstitial cells of Cajal) or their progenitor cells. Spontaneous tumors have been reported in dogs, horses, rhesus, and a ch…

BackgroundPrimary neuroendocrine carcinomas of the liver have rarely been reported in humans and domestic animals, but not in non-human primates.MethodsWe describe the morphologic and immunohistochemical features of a primary hepatic neuroe…

BACKGROUND: Marmosets and tamarins are increasingly used in research, but their pathology remains poorly defined compared with Old World primates. METHODS: Necropsy records of 129 marmosets and 52 tamarins were reviewed; none was used expe…

BackgroundIn baboons, Papio sp. neoplasms tend to affect the hematopoietic system most commonly, with rare documentation of myxomatous neoplasms. In contrast, women can develop myxomatous masses within deep peripelvic tissues with some freq…

Adenomyosis is a non-neoplastic condition characterized by the presence of ectopic endometrium in the myometrium with hyperplasia of adjacent smooth muscle. Common symptoms in women include debilitating pelvic pain and abnormal uterine blee…

The baboon is an established model for endometriosis research. This report describes the occurrence of spontaneous endometriosis involving the ileocaecal junction and associated regional lymph nodes in the baboon. All endometriotic foci lac…

ObjectiveTo determine whether an association exists between the histopathologic diagnosis of adenomyosis and infertility in a population of captive baboons.DesignCase-control study.SettingSouthwest National Primate Research Center.Animal(s)…

Spontaneous endometriosis was diagnosed in 43 baboons over a 14-year period. Thirty-seven have died; five remain alive; one was sold and lost to follow-up. The average age at diagnosis was 17.2 years; 29 (67%) were between 12 and 21 years o…

Twelve spontaneous ovarian tumors were found in the Southwest Foundation for Biomedical Research baboon colony. These included four granulosa cell tumors, three teratomas, two endometrioid carcinomas, one seromucinous cystadenofibroma, a cy…

Endometriosis was histologically confirmed in 70 female rhesus monkeys (Macaca mulatta). Severity of endometriosis was staged as minimal (14% of the monkeys), moderate (20%), or massive (66%). Clinical examination indicated masses in the ab…

An adult female Macaca fascicularis developed anorexia and minimal fecal production. Abdominal palpation was unrewarding. Rectal palpation revealed a rectal stricture and a large soft tissue mass in the area of the uterus. Clinical patholog…