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Hypertensive disorders of pregnancy (HDP) remain a leading cause of maternal and perinatal morbidity worldwide, and current screening strategies have limited predictive value in low-risk populations especially for late-onset HDP. This study…
BackgroundChronic pain is a common, poorly understood condition. Genetic studies including genome-wide association studies have identified many relevant variants, which have yet to be translated into full understanding of chronic pain. Tran…
BackgroundOvarian tissue cryopreservation has been proven to preserve fertility against gonadotoxic treatments. It has not been clear how this procedure would perform if planned for slowing ovarian aging.ObjectiveThis study aimed to determi…
IntroductionOvarian cancer is the seventh most prevalent cancer among women. It has high mortality and morbidity and imposes a great burden on healthcare systems worldwide. Unraveling the mechanisms behind the Epithelial-Mesenchymal Transit…
Cathepsins are powerful proteases, once referred to as the lysosomal cysteine proteases, that have been implicated in breast cancer invasion and metastasis, but pharmaceutical inhibitors have suffered failures in clinical trials due to adve…
Objective: In-office NovaSure® after Essure® is a clinical paradigm for which physicians are seeking information. A PubMed search (July 2011) revealed no peer-reviewed articles describing this treatment sequence. To address the paucity of d…
IntroductionThe purpose of this report is to evaluate our experience with transvaginal application of a laparoscopic bipolar cutting forceps to assist vaginal hysterectomy in extremely obese women with endometrial cancer in whom obesity pre…
Data are presented on establishing pregnancies by IVF during 1987 using only clomiphene citrate and human menopausal gonadotrophin for follicular stimulation. Of the 562 patients undergoing follicular stimulation, 80% reached oocyte recover…
The application of nuclear magnetic resonance imaging to the diagnosis of ovarian tumours has been studied in a group of seven patients with ovarian masses and several healthy volunteers who provided examples of normal pelvic anatomy. In th…