Dingmin Yan

No ORCID on file · 12 papers in corpus · active 2016-2026

Study types

  • article 10
  • other 1
  • review 1

Condition tags

  • endometriosis 12
  • mesh:D004715 8
  • endometrioma 2
  • adenomyosis 2
  • dysmenorrhea 1
  • mesh:D017699 1
other 2026
Impaired PIEZO1 function drives uterine hypercontractility in adenomyosis-associated dysmenorrhea
Human reproduction open ·doi:10.1093/hropen/hoag013

STUDY QUESTION: Does PIEZO1 play any role in adenomyosis-associated dysmenorrhea? SUMMARY ANSWER: PIEZO1 downregulation in the myometrium reduces the expression of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) production, …

article 2023
Shorter Anogenital Distance in Women with Ovarian Endometriomas and Adenomyosis, but Not Uterine Leiomyomas
Biomedicines ·doi:10.3390/biomedicines11102618

We investigated whether anogenital distance (AGD) is associated with adenomyosis, endometriosis and uterine leiomyomas (UL, also called uterine fibroids). We recruited 81 women with UL, 105 with ovarian endometrioma (OE), 116 with adenomyos…

article 2022
Tetramethylpyrazine Stalls Lesional Progression via Inducing Senescence in Mouse with Induced Deep Endometriosis
·doi:10.18103/mra.v10i11.3341

So far, the pressing need for the development of non-hormonal therapeutics for endometriosis has been unfulfilled. In light of the evidence that platelets play important roles in the development of endometriosis and that tetramethylpyrazine…

article 2020
Mesothelial Cells Participate in Endometriosis Fibrogenesis Through Platelet-Induced Mesothelial-Mesenchymal Transition
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa550

CONTEXT: While fibrosis in endometriosis has recently loomed prominently, the sources of myofibroblasts, the principal effector cell in fibrotic diseases, remain largely obscure. Mesothelial cells (MCs) can be converted into myofibroblasts …

article 2020
Platelets induce endothelial–mesenchymal transition and subsequent fibrogenesis in endometriosis
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2020.03.020
article 2020
Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2020.04.006
article 2019
Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis
Scientific reports ·doi:10.1038/s41598-019-39170-w

Endometriotic lesions are known to be hyperinnervated, especially in lesions of deep endometriosis (DE), which are frequently in close proximity to various nerve plexuses. DE lesions typically have higher fibromuscular content than that of …

article 2019
Platelets drive fibrogenesis through induction of endothelial-mesemchymal transition (EndoMT) in endometriosis
·doi:10.1016/j.fertnstert.2019.07.327
article 2018
Sensory nerve-derived neuropeptides accelerate the development and fibrogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/dey392

STUDY QUESTION: Do sensory nerves play any role in the development of endometriosis? SUMMARY ANSWER: Sensory nerves participate in all major steps (epithelial-mesenchymal transition (EMT), fibroblast-to-myofibroblast transdifferentiation (F…

article 2018
The establishment of a mouse model of deep endometriosis
Human Reproduction ·doi:10.1093/humrep/dey361

STUDY QUESTION: Is it possible to establish a mouse model of deep endometriosis (DE)? SUMMARY ANSWER: A mouse DE model that is macroscopically and microscopically similar to nodular lesions in humans can be constructed in as short as 3 week…

article 2016
Endometriosis-Derived Thromboxane A2 Induces Neurite Outgrowth
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116670037
review 2016
Nerve fibers and endometriotic lesions: partners in crime in inflicting pains in women with endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2016.06.017