Gogacz M

OBJECTIVES: Endometriosis presents a multitude of challenges for individuals. Current treatment of the disease is based on pharmacotherapy that aims to relieve pain, improves future fertility, potentially slows disease progression and lesse…

BackgroundTo date, a limited number of endometriosis cases occurring before or around the time of menarche have been documented.CaseAn 11-year-old adolescent underwent an emergency operation for left ovarian endometrioma. Her menarche occur…

OBJECTIVES: Tumor necrosis factor-alpha (TNF-alpha) plays a key role in the processes underlying the development of pelvic endometriosis. TNF-alpha acts on target cells via two receptors: TNFR1(p55) and TNFR2(p75). Depending on cell type an…

INTRODUCTION: Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis. MATERIAL AND METHODS: In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8…

ObjectiveChanges in peritoneal fluid (PF) composition may affect fertilization as well as early embryonic development. Leptin, an adipocyte hormone, has been shown to act as a link between adipose tissue and the reproductive system. Therefo…

Leptin may play a role in the regulation of menstrual cycle acting either directly on ovaries or at the level of the hypothalamic-pituitary axis. Peritoneal fluid is a biologically active environment that influences ovarian function but, on…

Phagocytic activity of macrophages isolated from peritoneal fluid (PF) was estimated using flow cytometry. Study group consists of 28 patients with endometriosis and 19 patients with benign noninflammatory tumour of adnex(is) served as refe…

Dendritic cells represent discrete leukocyte subpopulation of specialist or "professional" antigen-presenting cells (APC). They play a crucial role in the activation of naive T cells "in vivo" They have monocyte/macrophages origin. There ar…

ObjectiveTo determine whether impairment of the antioxidant systems of peritoneal fluid might be a factor responsible for infertility.Study designTotal antioxidant status was measured in peritoneal fluid obtained from 18 infertile women suf…

OBJECTIVE: To estimate the concentration of malonyldialdehyde (MDA) and total antioxidant status in the peritoneal fluid (PF) of patients with unexplained infertility (UI) and infertile women with minimal and mild endometriosis. MATERIALS A…

The presence of leukocyte subpopulations was demonstrated in peritoneal fluid and in endometrial tissue of women with (n = 16) and without (n = 20) endometriosis. Peritoneal fluid samples were also assayed for effects on lymphocyte prolifer…