Yutaka Osuga

No ORCID on file · 270 papers in corpus · active 1995-2026

Study types

  • article 198
  • other 29
  • review 13
  • preprint 10
  • book-chapter 7

Condition tags

  • endometriosis 201
  • adenomyosis 54
  • endometrioma 38
  • dysmenorrhea 28
  • infertility 24
  • chronic_pelvic_pain 11
  • dyspareunia 5
  • bowel_endometriosis 4
  • bladder_endometriosis 3
  • mesh:D004716 3
other 2017
Long-term use of dienogest in the treatment of painful symptoms in adenomyosis
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13406

AIM: We aimed to investigate the safety and efficacy of dienogest (DNG), a progestational 19-norsteroid, administered for 52 weeks in patients with symptomatic adenomyosis. METHODS: A total of 130 patients with adenomyosis received 2 mg of…

other 2017
Mannose receptor is highly expressed by peritoneal dendritic cells in endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.09.036

OBJECTIVES: To characterize peritoneal dendritic cells (DCs) in endometriosis and to clarify their role in its etiology. DESIGN: Experimental. SETTING: University hospital. PATIENT(S): Sixty-three women (35 patients with endometriosis an…

article 2017
Negative impact of adenomyosis on blood level of AMH
article 2017
Periostin activates invasive potency of endometriotic epithelial cells
article 2017
Preoperative assessment of factors associated with difficulty in performing total laparoscopic hysterectomy
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13198

AIM: Our objective was to determine the preoperative factors associated with difficulty in total laparoscopic hysterectomy (TLH). METHODS: This retrospective clinical study included 157 patients who underwent TLH for leiomyoma or adenomyosi…

article 2017
Relugolix, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist, in women with endometriosis (EM)-associated pain: Phase 2 safety and efficacy 24-week results
·doi:10.1530/endoabs.49.gp134

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

article 2017
Resveratrol suppresses inflammatory responses of peritoneal macrophages in endometriosis
article 2017
Snail promotes invasion and inflammatory reactions in endometriotic epithelial cells
article 2017
The activation of PI3K/Akt/mTOR pathway is associated with the activation of primordial follicles in ovaries affected with endometrioma
article 2017
The expression and significance of “danger signal” IL-33 system in endometriosis
·doi:10.1016/j.jri.2017.10.025
article 2017
The role of peritoneal macrophages in the pathogenesis of endometriosis
article 2016
Alpha‐7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12592

OBJECTIVE: We investigated α-7 nAchR expression in human peritoneal macrophages and examined whether activation of nAchR might be a new therapy for endometriosis. MATERIALS AND METHODS: Human peritoneal fluid mononuclear cells (PFMC) were s…

article 2016
Assisted reproductive technology pregnancy complications are significantly associated with endometriosis severity before conception: a retrospective cohort study
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-016-0209-2

BACKGROUND: Endometriosis has been shown to be associated with second- to third-trimester pregnancy complications such as preterm birth and placenta previa, but the evidence is inconsistent. We hypothesized that endometriosis severity might…

article 2016
Deep endometriosis infiltrating
other 2016
Development of ovarian cancer after excision of endometrioma
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.07.1077

OBJECTIVE: To determine the prevalence rate of subsequent development of ovarian cancer after excision of endometrioma. DESIGN: Retrospective cross-sectional study. SETTING: University hospital. PATIENT(S): A total of 485 women with endo…

article 2016
Dienogest reduces nerve growth factor expression in human adenomyosis
·doi:10.1016/j.jri.2016.04.184
article 2016
Dienogest reduces nerve growth factor expression in human adenomyosis
·doi:10.1016/j.jri.2016.04.016
article 2016
Dienogest reduces proliferation, NGF expression and nerve fiber density in human adenomyosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2016.10.053
article 2016
Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells
Journal of reproductive immunology ·doi:10.1016/j.jri.2016.12.002
article 2016
Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1515

CONTEXT: Endometriosis is an estrogen-dependent, chronic inflammatory disease. Recent studies have shown that vitamin D (VD) is an effective modulator of the immune system and plays an important role in controlling many inflammatory disease…

article 2016
Expressions of Ninjurin-1 in endometriosis and adenomyosis
·doi:10.1016/j.jri.2016.04.241
article 2016
Expressions of Ninjurin-1 in endometriosis and adenomyosis
·doi:10.1016/j.jri.2016.04.073
article 2016
ISP-31-9 Analgesic effects of levonorgestrel-releasing intrauterine system (LNG-IUS) on patients with and without adenomyosis(Group 31 Endometriosis,International Session Poster)
article 2016
ISP-32-3 Hysterectomy does not change recurrence rate of ovarian endometrioma after cystectomy(Group 32 Endometriosis/Endometrium,International Session Poster)
article 2016
ISP-32-5 Anti-inflammatory effects of drospirenone on endometriosis(Group 32 Endometriosis/Endometrium,International Session Poster)