Yutaka Osuga

No ORCID on file · 270 papers in corpus · active 1995-2026

Study types

  • article 198
  • other 29
  • review 13
  • preprint 10
  • book-chapter 7

Condition tags

  • endometriosis 201
  • adenomyosis 54
  • endometrioma 38
  • dysmenorrhea 28
  • infertility 24
  • chronic_pelvic_pain 11
  • dyspareunia 5
  • bowel_endometriosis 4
  • bladder_endometriosis 3
  • mesh:D004716 3
article 2020
·doi:10.1016/j.fertnstert.2019.11.010
article 2020
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14244

AIM: Endometriosis mostly affects the ovary but can also be present outside of the ovary including the pelvic peritoneum, intestine, urinary tract and lung. In case of ovarian endometriotic cyst, an increased risk of ovarian cancer, especia…

article 2020
·doi:10.1016/j.jri.2020.103238
article 2020
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14522

The aim of this publication is to disseminate the clinical practice guidelines for the treatment of intestinal, bladder/ureteral, thoracic and umbilical endometriosis, already published in Japanese, to non-Japanese speakers. For developing …

article 2020
·doi:10.1177/1745506520952003

Administration of Dienogest prior to hysteroscopic polypectomy is empirically performed, but the physiological effects of Dienogest on endometrial polyps are unclear. We aimed to investigate the effects of Dienogest on the proliferation and…

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00041-4
review 2020
Reproductive medicine and biology ·doi:10.1002/rmb2.12340

BACKGROUND: Extra-pelvic endometriosis is a rare type of endometriosis, which occurs in a distant site from gynecological organs. The diagnosis of extra-pelvic endometriosis can be extremely challenging and may result in a delay in diagnosi…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00189-4

When the presence of endometriotic lesions are not evident by hematoxylin and eosin staining, CD10 is used to highlight and confirm the presence of endometriotic stroma. However, CD10 is not specific only to the endometrial stroma but is al…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00090-9

In endometriosis, M2 macrophages (MΦ) are dominant and promote the development of endometriosis lesions. However, the factor(s) which induces M2 MΦ are unknown. In the present study, we focused on interleukin (IL)-33, known as an alarmin an…

article 2020
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14209

AIM: To investigate the safety and efficacy of dienogest (DNG), a progestational 19-norsteroid, administered for 52 weeks in patients with primary and secondary dysmenorrhea. METHODS: A total of 147 patients with dysmenorrhea received 1 mg …

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00186-7
article 2020
Biomedicines ·doi:10.3390/biomedicines8110467

Background: Relaxin (RLX)-2, produced by the corpus luteum and placenta, is known to be potentially effective in fibrotic diseases of the heart, lungs, kidneys, and bladder; however, its effectiveness in endometriosis has not yet been inves…

article 2020
Fertility and sterility ·doi:10.1016/j.fertnstert.2020.07.055
article 2020
Journal of reproductive immunology ·doi:10.1016/j.jri.2020.103104
article 2020
Molecular human reproduction ·doi:10.1093/molehr/gaaa077

Non-hormonal therapeutic strategies for endometriosis are needed. The aim of this study was to characterize the effects of prostaglandin (PG)E2 receptor inhibitors to explore their potential as novel therapeutic strategies for endometriosis…

article 2019
Molecular human reproduction ·doi:10.1093/molehr/gaz066

Endometriosis exerts detrimental effects on ovarian physiology and compromises follicular health. Granulosa cells from patients with endometriosis are characterized by increased apoptosis, as well as high oxidative stress. Endoplasmic retic…

article 2019
article 2019
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2019.02.021
article 2019
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14059

AIM: This study aimed to describe the clinical presentation, diagnostic evaluation, and operative or medical management of inguinal endometriosis. METHODS: In this study, we retrospectively reviewed 20 cases of inguinal endometriosis in our…

review 2019
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology ·doi:10.1080/01443615.2018.1460584

We aimed to examine how leuprorelin has been studied for the treatment of women with endometriosis in Asia. We conducted a literature search of PubMed, the Cochrane Library and ClinicalTrials.gov. This review includes randomised trials of w…

article 2019
BMC women's health ·doi:10.1186/s12905-019-0760-z

BACKGROUND: The recurrence rate after unilateral salpingo-oophorectomy (USO) for unilateral endometrioma has not been reported. We evaluated the rate of and risk factors for endometrioma recurrence after USO. METHODS: In this retrospective …

case-report 2019
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2019.05.021

Desmoid tumors, which are often estrogen-dependent, frequently develop in surgical wounds. Here we report the case of 33-year-old woman with a 4-cm solid mass detected in her left adnexal area. She had previously undergone a laparoscopic su…

article 2019
Human Reproduction ·doi:10.1093/humrep/dez028

STUDY QUESTION: Does the GnRH antagonist, ASP1707, reduce endometriosis-associated pelvic pain? SUMMARY ANSWER: ASP1707 significantly reduced endometriosis-associated pelvic pain in a dose-related manner. WHAT IS KNOWN ALREADY: GnRH agonist…

article 2019
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2019-00281

CONTEXT: The ovarian reserve is reduced in patients with endometriosis. We hypothesize that the phosphatidylinositol 3-kinase (PI3K)-phosphatase and tensin homolog deleted on chromosome 10 (PTEN) Akt-Forkhead box O (Foxo3) pathway is involv…

article 2019
·doi:10.1016/j.fertnstert.2019.09.014