Michel Canis

The management of endometriosis related infertility requires a global approach. In this context, the prescription of an anti-gonadotropic hormonal treatment does not increase the rate of non-ART (assisted reproductive technologies) pregnanc…

In this chapter we have examined the possibilities of screening endometriosis, both in the general population as well as in the target population. We then proposed decision trees, for primary and secondary care. Currently, there is not enou…

The article presents French guidelines for surgical management of endometriosis. Surgical treatment is recommended for mild to moderate endometriosis, as it decreases pelvic painful complaints and increases the likelihood of postoperative c…

ObjectiveTo provide clinical practice guidelines for the management of painful endometriosis in women without infertility.MethodsSystematic review of the literature literature since 2006, level of evidence rating, external proofreading and …

ObjectiveTo report and visually demonstrate the feasibility of using indocyanine green (ICG) in endometriosis surgery and to discuss potential benefits.DesignICG fluorescent imaging has been validated to assess tissue perfusion with clinica…

OBJECTIVE(S): To compare the most used types of surgical techniques, for peritoneal lesions management, to Plasmajet® (PJ), in term of healing and post-operative adhesion. STUDY DESIGN: Prospective, experimental animal study. Female pigs (…

Endometriosis is defined as the presence of endometrial glands and stroma within extrauterine sites. Our previous study revealed an epithelial to mesenchymal transition (EMT)-like process in red peritoneal endometriosis, whereas membrane lo…

Endometriosis is a common gynecological disorder responsible for infertility and pelvic pain. A complete cure for patients with endometriosis awaits new targets and strategies. Here we show that U0126 (a MEK inhibitor) and MK2206 (an AKT in…

INTRODUCTION: Optimal surgical treatment of rectovaginal endometriosis remains a controversial topic. The objective of this study was to evaluate long-term postoperative outcomes after rectal shaving or colorectal resection for rectovaginal…

Preoperative evaluation: clinical examination, and research for associated lesions. Laparoscopic approach. Cystectomy: gold standard, conformed to the endometrioma pathophysiology (3 zones). Laser CO2 Plasmajet® vaporisation: important data…

IntroductionThe objectives were to evaluate the acceptability, reliability and validity of the cross-cultural adaptation of the Endometriosis Health Profile-30 instrument into French.MethodsThis cross-sectional study was conducted between J…

The purpose of the studyTo study preoperative thresholds of the SF-36 components above which we can predict a high risk of failure in order to improve the quality of life after surgery for patients with minimal endometriosis.Material and me…

ObjectiveThe study was performed to evaluate whether trauma is an initial event of development of endometriosis.MethodUsing Medline database from January 1960 up to December 2014, a systematic review was made of all published studies using …

L’adenomyose est encore aujourd’hui, largement enigmatique quant a son etiologie et a son rapport particulier avec l’endometriose. Son impact en tant que facteur d’infertilite, isole ou associe, est indeniable mais surement tres variable se…

Endometriosis is a common condition in women, whose main repercussions are painful symptoms. In addition, it was shown that endometriosis was a major cause of infertility and various obstetric complications could be related to this patholog…

La prise en charge chirurgicale des endometriomes est une situation frequente. En cas de symptomatologie clinique significative (douleurs notamment), la prise en charge chirurgicale est justifiee, en particulier en cas de resistance au trai…

Analysis of risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for ovarian endometriosis†

HOXA-10 expression in the mid-secretory endometrium of infertile patients with either endometriosis, uterine fibromas or unexplained infertility†

STUDY QUESTION: Can deep infiltrating endometriotic stromal cells (DES) sense changes in extracellular matrix (ECM) stiffness and respond to them? SUMMARY ANSWER: Soft matrices inhibit cell proliferation and inactivate the fibrotic phenotyp…