Jacek Szamatowicz

It has been well documented that aberrant expression of selected microRNAs (miRNAs) might contribute to the pathogenesis of disease. The aim of the present study is to compare miRNA expression by the most comprehensive locked-nucleic acid (…

ObjectiveTo determine the concentrations of cathepsins B, D and G in proliferative eutopic endometrium of patients with and without endometriosis, by use of the surface plasmon resonance imaging (SPRI) technique.Study designA total of 55 pa…

BACKGROUND: The eutopic endometrium of women with endometriosis, compared with disease-free individuals, contains certain molecular alterations, including the differential expression of microRNA (miRNA). The aim of the study was to compare …

ObjectiveTo compare the expression level of the most relevant angiogenesis-related genes in the eutopic endometrium of women with and without endometriosis.Study design32 regularly menstruating patients (18 with endometriosis and 14 control…

BACKGROUND: It is becoming increasingly evident that the eutopic endometrium of women with endometriosis shows certain genetic alterations which are not found in the endometrium of disease-free women. The aim of the study was to compare the…

PURPOSE: Chemokines play essential role not only in controlling leukocyte function and trafficking but also in the angiogenesis and modulation of inflammatory responses. MATERIAL AND METHODS: A novel array-based enzyme-linked immunosorbent …

OBJECTIVE: It is becoming more and more evident that different types of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in the pathogenesis of endometriosis. The aim of the present study was to measure leve…

Endometriosis is a common disease in women at reproductive age. We investigated the concentration of neutrophil-activating factor (growth-regulated gene-alpha; GRO-alpha) (a member of the chemokine family), in peritoneal fluid of infertile …

AbstractEndometriosis is a common disease in women at reproductive age. We investigated the concentration of neutrophil-activating factor (growth-regulated gene-α; GRO-α) (a member of the chemokine family), in peritoneal fluid of infertile …

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of endopeptidases which play a role in the degradation and turnover of extracellular matrix proteins. Their action is regulated by specific tissue inhibitors called tissue inhibitors…

OBJECTIVES: Disturbances in topical immunological response during endometriosis, cell and humoral, is of particular interest nowadays. Increase in the number and activity of peritoneal macrophages depends to a large extent on calcium concen…

Adhesive molecules have played an important and well-established role in cell-to-cell communication for a long time. They reveal specific functions in an ongoing disturbed immunological reactions, including endometriosis. This review is to …