Sutrisno Sutrisno

Objective: To analyze the inhibitory effect of genistein on matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) through inhibition of nuclear factor-kappa B (NF-κB) activation. Methods: A total of 36 female mice were d…

Objectives: This study aimed to observe the difference in the area of endometriosis lesions and the histopathology of inflammatory cells and granuloma masses in an endometriosis mouse model treated with endometrial cell implants, endometrio…

> 0.05). It was concluded that genistein is able to modulate estrogen receptor-α and estrogen receptor-β and inhibit the development of inflammation and angiogenesis in the murine model of peritoneal endometriosis. Thus, genistein can be a …

This research aimed to investigate the effect of genistein on TGF-β, dysregulation of apoptosis, NF-κB pathway, COX-2 pathway in mice of endometriosis model. Twenty-eight female mice (Mus musculus) were divided into seven groups (n = 4), in…

This in silico and in vivo investigation were to know the effect of genistein on alteration of MMPs in a mice model of endometriosis. Forty female mice (Mus musculus) were divided into eight groups (n=5 each), including the control (untreat…

This study aimed to investigate whether the genistein is able to decrease the expressions of vascular endothelial growth factor-A (VEGF-A) and hypoxia inducible factor-1α (HIF-1α) in mouse model of endometriosis. Forty female mice (Mus musc…

To investigate the effect of genistein on proinflammatory cytokines, NF-κ B activation, and estrogen receptor-β expression in a mice model of endometriosis. Forty female mice (Mus musculus) were divided into eight groups (n=5 each), includi…

Genistein adalah salah satu terapi untuk endometriosis. Penelitian ini bertujuan untuk membuktikan pengaruh pemberian genisteindosis tinggi terhadap ekspresi protein Ki-67 pada kultur sel endometriosis. Penelitian eksperimental ini dilakuka…

Genistein merupakan salah satu terapi untuk endometriosis. Penelitian ini bertujuan mengetahui pengaruh pemberian berbagaidosis genistein terhadap apoptosis sel pada kultur sel endometriosis. Ini merupakan penelitian eksperimental dengan Tr…

Terapi genistein dikembangkan karena bersifat anti-estrogenik, berfungsi sebagai antioksidan, inhibitor proliferasi, dan anti-kanker.Tujuan penelitian ini adalah menganalisa pengaruh genistein berbagai dosis dan waktu inkubasi terhadap penu…

Genistein adalah salah satu terapi untuk endometriosis. Penelitian ini bertujuan mengetahui pengaruh genistein terhadap penurunankadar TNF-α dan IL-6 pada kultur jaringan endometriosis. Penelitian ini dilakukaan di Laboratorium Fisiologi Fa…

To investigate whether genistein is anti-inflammation and anti-angiogenesis in endometriosis cells. Primary endometriosis cells were divided into seven groups, including control group and genistein-treatment group at dose 5 until 50 μmol/L.…

Objectives: This study aimed to investigate whether genistein is able to inhibit cell proliferation and expression of estrogenic receptors, and to induce apoptosis in endometriosis cells. Methods: Confluent primary endometriosis cells were…