I Wayan Agung Indrawan

article 2024

Molecular docking of flavonoids from Phaleria macrocarpa on the NF-kB p65, VEGFR2, Ki67, COX-2, and CXCR4 pathways in endometriosis

·doi:10.56499/jppres24.2090_13.2.527

Context: Endometriosis is a condition marked by the presence of endometrial epithelium and stromal cells outside the uterus. Previous studies have shown that prostaglandin E2 has a role in the development of endometriosis via the action of …

article 2023

Comparison of the Effects of Dienogest and Leuprolide Acetat on Serum Interferon (IFN-Ɣ) Levels in a Mouse Model of Endometriosis (Mus musculus)

·doi:10.55561/ajhr.v2i2.111

Introduction: Endometriosis is a medical condition in which there is abnormal growth of tissue resembling the endometrium outside the uterus. It can cause symptoms of pain and/or infertility. The current medical therapy focuses on reducing …

article 2023

Potential Of Mahkota Dewa Fruit (Phaleria macrocarpa) Flavonoids Extract and Dienogest to Reduce IL-17A Levels in Mice Endometriosis Model

·doi:10.31964/mltj.v9i2.536

Endometriosis is an inflammatory disease that occurs in glands outside the endometrium. Interleukin 17 (IL-17) is a proinflammatory cytokine degrading Th17 cells, which play an essential role in several inflammatory diseases. IL-17 expressi…

article 2023

The Effect of Flavonoid from Extract of Phaleria Macrocarpa on Levels Il-2, Il-17a and Il-33 in Endometriosis Mice

·doi:10.17762/jaz.v44i3.1156

Endometriosis is a inflamatory disease especially in the state of reproductive age. Phaleria macrocarpa is a plant that has a population in Papua, Irian Jaya. Endometriosis therapies available have still many weakness, including being expen…