Sevtap Kılıç

PurposeThe aim of this study was to test if melatonin causes regression of endometriotic implants and whether it influences implant levels of superoxide dismutase (SOD), malondialdehyde (MDA), vascular endothelial growth factor (VEGF), tiss…

Aim Angiogenesis plays an important role in the pathogenesis of endometriosis. Thus, the inhibition of angiogenesis may prevent endometriosis. Bevacizumab is a recombinant humanized monoclonal antibody against VEGF. The aim of this study is…

ObjectiveTo determine the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in the rat endometriosis model.Study designA randomized, placebo-controlled, blinded study using rat endometriosis model. After…

ObjectiveTo show the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in an experimental model.DesignA randomized, placebo-controlled, blinded study using rat endometriosis model.SettingExperimental res…

Endometriotic implants were induced surgically in female Wistar albino rats, which were randomly divided into three groups. The rats in group I (n=10) and group II (n=9) were given 2.5 mg/kg/day intraperitoneal and oral atorvastatin, respec…

ObjectiveWe sought to test if metformin could regress endometriotic explants in rats.Study designAfter inducing endometriotic implants and randomization of female Wistar albino rats, they were given 25 and 50 mg/kg/day of oral metformin in …

The aim of the research was to reveal vascular endothelial growth factor (VEGF) immunolocalization in endometrioma cysts and endometrial tissues. The study group (group1) included 15 patients laparoscopically operated on for endometrioma an…