Jie Chen

No ORCID on file · 25 papers in corpus · active 2011-2026

Study types

  • article 13
  • other 10
  • review 2

Condition tags

  • endometriosis 23
  • infertility 4
  • dysmenorrhea 2
  • chronic_pelvic_pain 1
  • endometrioma 1
  • adenomyosis 1
  • dyspareunia 1
article 2026
·doi:10.1016/s0016-5085(26)02579-5
article 2026
·doi:10.1016/s0016-5107(26)02510-1
article 2025
·doi:10.1016/j.jmig.2025.09.508
other 2025
BMC women's health ·doi:10.1186/s12905-025-04237-6

OBJECTIVE: This study aimed to investigate the causal relationship between dietary habits and nine common diseases with high female prevalence using a two-sample Mendelian randomization (MR) approach. METHODS: Drawing upon pooled Genome-Wi…

other 2025
American journal of translational research ·doi:10.62347/PGYY9493

OBJECTIVE: While physical activity (PA) patterns are epidemiologically linked to gynecologic pathologies, establishing causality remains uncertain. This Mendelian randomization (MR) study evaluated causal relationships between PA phenotypes…

article 2025
Cell proliferation ·doi:10.1111/cpr.13800

Ovarian endometrioma (OEM), a particularly severe form of endometriosis, is an oestrogen-dependent condition often associated with pain and infertility. The mechanisms by which OEM impairs fertility, particularly through its direct impact o…

other 2025
Cureus ·doi:10.7759/cureus.77341

OBJECTIVE: The present study was designed to comprehensively analyze the expression profiles of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α), estrogen-related receptor-α (ERRα), estrogen receptor-β (ERβ), interleukin…

article 2025
Biochemical and biophysical research communications ·doi:10.1016/j.bbrc.2025.151964
article 2023
Journal of biomedical research ·doi:10.7555/jbr.37.20230095

Endometriosis is defined as a condition with endometrium-like tissues migrating outside of the pelvic cavity. However, the mechanism of endometriosis is still unclear. Lactate can be covalently modified to lysine residues of histones and ot…

review 2023
·doi:10.31083/j.ceog5008164

Objective: Ligustrazine is an amide alkaloid, with the active substance being Chuanxiong. Also known as tetramethylpyrazine (TMP), ligustrazine has various pharmacological effects and has been used to treat a variety of diseases. Many studi…

article 2022
Frontiers in pharmacology ·doi:10.3389/fphar.2022.985618

Endometriosis is a common gynecological disease, characterized by the presence of endometrial-like lesions outside the uterus. This debilitating disease causes chronic pelvic pain and infertility with limited therapeutics. Chemerin is a sec…

article 2021
World journal of clinical cases ·doi:10.12998/wjcc.v9.i30.9122

BACKGROUND: Accessory and cavitated uterine mass (ACUM) is an uncommon form of connate Müllerian anomaly seen in young and nulliparous women, which presents as chronic periodic pelvic pain and severe dysmenorrhea. The entity is often underd…

other 2019
Medicine ·doi:10.1097/MD.0000000000015137

AIMS: To investigate the association between polymorphism in the gene encoding the epidermal growth factor receptor (EGFR) and susceptibility to endometriosis among women in southwest China. METHODS: A case-control study involving 201 endo…

article 2018
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology ·doi:10.1159/000489753

BACKGROUND/AIMS: Ovarian endometriosis (OvE) is ovarian cyst that is lined with endometrial tissue. They are found in 17-44% of women with endometriosis. Their clinical manifestations include pelvic pain, dysmenorrhea, dyspareunia, and infe…

article 2018
Molecular medicine reports ·doi:10.3892/mmr.2018.9341

Endometriosis is a common gynecological disease and the pathogenesis is not clearly understood. Previous studies have demonstrated via microarray techniques that microRNA (miR)‑449b was significantly downregulated both in ectopic and eutopi…

other 2016
Medicine ·doi:10.1097/MD.0000000000003003

Ovarian clear cell carcinoma (CCC) is a distinct histologic subtype with relatively poor survival. No prognostic or predictive molecular marker is currently available. Recent studies have shown that AT-rich interactive domain 1A (ARID1A) an…

article 2016
Gynecologic oncology ·doi:10.1016/j.ygyno.2016.10.009
other 2016
Oncotarget ·doi:10.18632/oncotarget.7216

OBJECTIVES: The present study investigated the clinical implications of pretreatment carbohydrate antigen 125 (CA-125) levels and CA-125 normalization in patients with ovarian clear cell carcinoma (CCC), and it provides useful information f…

other 2015
BioMed research international ·doi:10.1155/2015/340218

We applied in the previous study miRNA microarray screening analysis to identify several differentially expressed miRNAs, including miR-183 in normal, eutopic, and ectopic endometrium. Knockdown of miR-183 expression induced the invasivenes…

other 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.08.008

OBJECTIVE: To analyze and compare the clinicopathological features and prognosis of ovarian clear cell carcinoma (CCC) with or without endometriosis in Chinese patients. DESIGN: Comparative study based on a retrospective review of medical …

other 2014
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/IGC.0000000000000275

OBJECTIVE: This study aimed to analyze the clinicopathological features of pure and mixed-type ovarian clear cell carcinoma (CCC) in Chinese patients. METHODS: Patients with ovarian CCC treated in our institution between 1982 and 2012 were…

article 2013
International journal of molecular medicine ·doi:10.3892/ijmm.2013.1536

Endometriosis is a common gynecological disease, yet its pathogenesis remains poorly understood. Recent studies have demonstrated that the aberrant expression of certain microRNAs (miRNAs) may correlate with the development and progression …

article 2013
Experimental and therapeutic medicine ·doi:10.3892/etm.2013.1458

Endometriosis is a common disease in females of reproductive age and has the classic characteristic of mononuclear cell infiltration into lesions. Shikonin is an anti‑inflammatory phytocompound obtained from Lithospermum erythrorhizon whose…

review 2012
Obstetrics and gynecology ·doi:10.1097/aog.0b013e31824da6fe

BACKGROUND: Clear-cell carcinoma transformed from an abdominal wall scar is extremely rare; there are only 22 cases reported in literature. Here we report a case of a patient with clear-cell carcinoma of the abdominal wall after cesarean de…

other 2011
Zhonghua yi xue za zhi

OBJECTIVE: To investigate the prevalence of infertility and its risk factors in the fertile-age couples of Beijing, China. METHODS: A cross-sectional survey on the prevalence and risk factors was conducted from July 2007 to May 2008 in 7 B…