HOX transcript antisense intergenic RNA (HOTAIR) is classically definedas an intracellular long non-coding RNA that scaffolds PRC2/LSD1 to remodel chromatin and functions as a competing endogenous RNA. Its detection in extracellular vesicle…
Following the initial treatment of nasopharyngeal carcinoma (NPC), tumor progression often portends an adverse prognosis for these patients. MicroRNAs (miRNAs) have emerged as critical regulators of tumor immunity, yet their intricate mecha…
BACKGROUND: Macrophage M2 polarization plays a critical role in the progression of endometriosis (EMS), and glycolysis has emerged as a potential therapeutic target. This study aimed to investigate the interplay between glycolytic signaling…
Endometriosis (EMS) is a chronic gynecological disease. RND3 is recognized as a potential autophagy-related biomarker in EMS. The aim of this study was to investigate the regulatory role of RND3 on autophagy and oxidative stress in EMS. Imm…
BACKGROUND: Intrauterine device (IUD) migration leading to vesicouterine fistula (VUF) with vesical calculi is rare. This case is notable due to the absence of typical Youssef’s syndrome symptoms and the insidious presentation of a Type III…
BACKGROUND: Female fertility declines with increased maternal age, and this decline is even more rapid after the age of 35 years. Follicular fluid (FF) is a crucial microenvironment that plays a significant role in the development of oocyte…
Severe acute pancreatitis (SAP) is a critical illness characterized by a severe systemic inflammatory response resulting in persistent multiple organ failure and sepsis. The intestinal microbiome is increasingly appreciated to play a crucia…
Objective:To explore the clinical efficacy of levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of adenomyosis.Methods:94 cases with adenomyosis were treated with LNG-IUS,and the menstrual blood volume,degree of dysmen…
Objective:To investigate microvessel density(MVD) and the matrix metalloproteinase inhibitor RECK expression in the ectopic endometrium and eutopic endometrium,explore the effect and significace of the matrix metalloproteinase inhibitor REC…
Objective:To investigate the expression and clinical significance of MMP-2,MMP-9 and RECK in endometriosis.Methods:The expression of MMP-2,MMP-9 and RECK in the ectopic endometrium from 48 patients with endometriosis and the eutopic endomet…