PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis

Han Li, Li Han, Xiaoshan Chai
Cellular signalling · 2025 · vol. 134 , pp. 111922 · doi:10.1016/j.cellsig.2025.111922 · PMID:40480430 · W4411022982
article OA: closed CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

PDPK1 regulates M2 polarization in macrophages through a hypoxia-induced CD47/AKT-glycolytic pathway, offering insights into endometriosis pathogenesis.

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Condition tags

endometriosis

MeSH descriptors

3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases 3-Phosphoinositide-Dependent Protein Kinases CD47 Antigen CD47 Antigen CD47 Antigen CD47 Antigen CD47 Antigen CD47 Antigen CD47 Antigen CD47 Antigen

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (47)

Cited by (2)

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-17T00:31:17.195017+00:00
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