Mihara Y

No ORCID on file · 7 papers in corpus · active 2017-2023

Study types

  • article 2
  • other 1
  • rct 1

Condition tags

  • endometriosis 3
  • endometrioma 3
  • infertility 1
article 2023
Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas
Reproductive medicine and biology ·doi:10.1002/rmb2.12548

PURPOSE: To test the theory that invaginated ovarian surface epithelium and endometrial implants on the ovary form ovarian endometriomas. METHODS: Adhesion sites of ovarian endometrioma on the peritoneum and consecutive ovarian endometriom…

2022
Effects of Melatonin on the Transcriptome of Human Granulosa Cells, Fertilization and Blastocyst Formation.
International journal of molecular sciences ·doi:10.3390/ijms23126731

Melatonin is a promising reagent that can improve assisted reproductive technology (ART) outcomes in infertility patients. However, melatonin is not effective for all infertile patients, and it remains unclear for which patients melatonin w…

2021
Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies.
Reproductive medicine and biology ·doi:10.1002/rmb2.12382

PurposeWe investigate the relationships between oocyte developmental capacity and follicular size of its origin in Japanese women: those undergoing conventional IVF (cIVF) and ICSI, respectively.MethodsA total of 3377 follicles were punctur…

article 2020
An Integrated Genomic Approach Identifies HOXC8 as an Upstream Regulator in Ovarian Endometrioma
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa618

PURPOSE: To identify the upstream regulators (URs) involved in the onset and pathogenesis of ovarian endometrioma. METHODS: Recently, a method called Significance-based Modules Integrating the Transcriptome and Epigenome (SMITE) that uses t…

other 2019
Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometrioma
Journal of ovarian research ·doi:10.1186/s13048-019-0489-1

BACKGROUND: In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic endometrium (EE). For example, in OE, the expressions of estrogen recepto…

rct 2019
The clinical outcome of Dienogest treatment followed by in vitro fertilization and embryo transfer in infertile women with endometriosis
Journal of ovarian research ·doi:10.1186/s13048-019-0597-y

BACKGROUND: Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro fertilization and embryo transfer (IVF-ET) is an important strategy for im…

2017
Thin endometrium transcriptome analysis reveals a potential mechanism of implantation failure.
Reproductive medicine and biology ·doi:10.1002/rmb2.12030

AimAlthough a thin endometrium has been well recognized as a critical factor in implantation failure, little information is available regarding the molecular mechanisms. The present study investigated these mechanisms by using genome-wide m…