L.G. Pivazyan

Benign uterine diseases remain among the leading causes of surgical interventions in women of reproductive age. A forty-year cumulative clinical experience (1986—2026) demonstrates that the effectiveness of reconstructive and uterus-preserv…

Objective.To summarize current knowledge on the effectiveness of antioxidant therapy in endometriosis treatment. Materials and Methods.A systematic review was conducted per PRISMA guidelines and registered in PROSPERO 2023 CRD42023454705.St…

Endometriosis is a gynecological disorder characterized by the presence of tissue that is morphologically and functionally similar to the endometrium, but located outside the uterine cavity. The disease is chronic and prone to recurrence. A…

This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted on PubMed, Cochrane L…

Endometriosis is a gynecological disorder characterized by the presence of endometrium-like tissue outside the uterine cavity and, in many cases, by a chronic and recurrent clinical course. This review synthesizes current evidence on the ge…

The article focuses on the of methods for objectifying pain syndrome in patients with endometriosis. Endometriosis-related pain, including dysmenorrhea, dyspareunia, and chronic pelvic pain, is a clinically significant symptom of the diseas…

The aim of this review is to analyse contemporary scientific evidence concerning the role and significance of macrophage polarisation in the pathogenesis of endometriosis. Particular emphasis is placed on the molecular and cellular mechanis…

Abnormal uterine bleeding (AUB) is bleeding that is excessive in frequency, duration and/or volume of blood loss compared to normal menstruation. AUB is one of the most common gynecological problems and occurs in 3–30 % of women of reproduc…

• Endometriosis shows significant variation in its presentation and pathophysiology and is closely linked to fibrosis. • There is a critical need to provide insights in pathophysiology of endometriosis and to find new biomarkers and targets…

Endometriosis is a gynecological disease characterized by the presence of tissue that is morphologically and functionally similar to the endometrium, but located outside the uterine cavity, with a chronic and recurrent course. According to …

Introduction. Endometriosis is an estrogen–dependent disease characterized by the spread of endometrial-like tissue outside the uterine cavity. Symptoms of the disease appear after menarche, in adolescence. The symptoms of endometriosis oft…

Endometriosis is a gynecological disease characterized by the presence of tissue with morphological and functional properties similar to the endometrium outside the uterine cavity. This pathology affects about 10% of women of reproductive a…

The purpose of this systematic review and meta-analysis was to determine iron metabolism markers in the peritoneal fluid (PF) of women with endometriosis. Search was conducted in electronic databases including PubMed, the Cochrane Library, …

The purpose of this systematic review was to identify potential metabolomic biomarkers of endometriosis in plasma, serum, peritoneal fluid, follicular fluid, urine, endometrial tissue samples of patients with endometriosis. Search was condu…

Pelvic floor disorders, including pelvic organ prolapse and urinary incontinence, benign and malignant genital diseases are common gynaecological problems faced by older women. With the rapidly growing population of active older women, phys…

Endometriosis is a gynecological disease that affects up to 10% of women of reproductive age and is characterized by pronounced heterogeneity of clinical manifestations and pathogenetic mechanisms. Despite significant advances in diagnostic…

Introduction. All current methods of hemostasis used in ovarian surgery inevitably lead to damage to healthy follicles. Significant loss of ovarian reserve in childhood can lead to the development of premature ovarian insufficiency in the f…

The article focuses on the role of oxidative stress, ferroptosis, and antioxidant therapy in the pathogenesis and treatment of endometriosis — a gynecological condition affecting up to 10% of women of reproductive age. Oxidative stress and …

Endometriosis is a benign gynecologic disease characterized by the presence of endometrial-like tissue outside the uterine cavity. The prevalence of this disease reaches 10—15 per cent among women of reproductive age. There is no single acc…

Microbiota is a collection of microorganisms present in a certain environment that participates in the ongoing processes of the body. The influence of the gut microbiota has become an exciting area of medicine. Now a large number of studies…

Introduction. Inflammatory diseases of the pelvic organs (IDPO) are common forms of pathology, which are often accompanied by serious complications. Aim: to determine the leading reproductive outcomes in adolescent girls with IDPO. Material…

Endometriosis is a common gynaecological disease that affects about 10% of women of reproductive age — approximately 200 million people worldwide. It is characterised by the presence of endometrium-like tissue outside the uterine cavity. En…