Agung Dewanto

This is a scoping review investigating awareness of general practitioners and midwives regarding early detection of endometriosis and its impact on diagnosis delay.

Introduction: Endometrium is one of the primary components of embryo to implant. Adequate endometrium is necessary for embryo to implant successfully. Inadequate endometrium increased the probability of unsuccessful embryonic implantation a…

Link of Video Abstact: https://youtu.be/noF1KQ1W7Sk Background: The tropomyosin kinase receptor B (TrkB) and p75 receptors may play a role in the formation of deep endometriosis and are related to the more intense pain in deep nodular endom…

This is a scoping review investigating screening tools for endometriosis and the limitation of their application

Background and Aims: Endometrioma occurs through the implantation of endometrial tissue in the ovary. The establishment of endometriotic lesions requires endometrial cells to invade the ovary by remodelling the extracellular matrix (ECM). I…

Background and Aims: Previous studies have explored the role of neurotrophins and their receptors, especially in forming deep endometriosis, endometriosis tissue invasion, and its effects on tissue proliferation. However, these studies do n…

BACKGROUND: Progestin therapy has been commonly used in endometriosis. The regulation of progesterone receptors B (PR-B) greatly affects the success rate of therapy in cases of endometriosis. The presence of tumor necrosis factor (TNF)-a in…

BACKGROUND: The invasion of endometrial tissue in the peritoneal layers is an important precursor to the formation of endometriosis. However, the mechanisms of the initial development of endometrioma remain unclear. This study aimed to expl…

Background. One of the fundamental pathogenesis of endometriosis to grow and develop is to carry out a cellular invasion of the surrounding tissue where it attaches. The invasion process of endometriotic focus is linked with the activity of…

genital tract, and placenta. Several gynecologic malignancies, such as endometrial and ovarian cancer, also highly express GnRH receptor. 8 However, information of endometriosis expression of GnRH receptor is still limited.

Latar belakang: Endometriosis merupakan penyakit yang ditandai adanya jaringan endometrium di luar cavum uterus, yang menimbulkan reaksi peradangan kronis. Gejala endometriosis paling sering adalah nyeri pelvis dan infertilitas. Endometrios…

Background: Endometriosis is a chronic condition that is influenced by the hormone estrogen which affects women of childbearing age, and is associated with pelvic pain and infertility. In Vitro Fertilization (IVF) is currently the most effi…

There are several limitations to assess immunohistochemical staining in the cells manually such as wide differences in the qualifications of researchers working with histological samples, infeasible to count every single cell, time consumin…

The ROIs were determined manually, separating glandular epithelial tissue and stromal tissue (a). The nuclear morphometric and staining parameter enable the identification in epithelial cells (b). Gray levels of separated â blue staining ch…

The ROIs were determined manually, separating glandular epithelial tissue and stromal tissue (a). The nuclear morphometric and staining parameter enable the identification in epithelial cells (b). Gray levels of separated â blue staining ch…

The selected endometriosis tissue required the presence of glandular epithelial cells and stromal cells. ROI were developed by selecting â customâ mode applied to separate lumen, epithelial gland tissue and stromal tissue. The lumen ROI was…

The selected endometriosis tissue required the presence of glandular epithelial cells and stromal cells. ROI were developed by selecting â customâ mode applied to separate lumen, epithelial gland tissue and stromal tissue. The lumen ROI was…

Markers determination. Nucleus identification was determined by selecting blue color as marker. First, the markers button was chosen. Hematoxillin staining button was chosen. Color picker button was chosen. Blue color taken from the cell th…

Markers determination. Nucleus identification was determined by selecting blue color as marker. First, the markers button was chosen. Hematoxillin staining button was chosen. Color picker button was chosen. Blue color taken from the cell th…

Setting parameter for nuclei size. The nucleus size was determined as depicted in Fig. 4a. It was based on blue color detection (hematoxylin staining). Brown color expressed by cell was restricted from interior radius −4,81 μm to exterior r…

Setting parameter for nuclei size. The nucleus size was determined as depicted in Fig. 4a. It was based on blue color detection (hematoxylin staining). Brown color expressed by cell was restricted from interior radius −4,81 μm to exterior r…

Scatter gram showing the result of hematoxylin staining (a) and DAB staining (b). The last step was determination of the immune positive or negative expression resulting from IHC staining. The â cut offâ option was used to set new values fo…

Scatter gram showing the result of hematoxylin staining (a) and DAB staining (b). The last step was determination of the immune positive or negative expression resulting from IHC staining. The â cut offâ option was used to set new values fo…

Manual counting of nerve fibers. Region of interests were selected randomly and marked with a border to obtain an area of 1Â mm2 each. A single nerve fiber was marked manually by using a tool available in HistoquestÂŽ software. (JPG 565Â kb…

Manual counting of nerve fibers. Region of interests were selected randomly and marked with a border to obtain an area of 1Â mm2 each. A single nerve fiber was marked manually by using a tool available in HistoquestÂŽ software. (JPG 565Â kb…