Jin L

STUDY OBJECTIVE: The aim of this study was to describe surgical outcomes after different types of colorectal surgery for bowel endometriosis and to present the feasibility of LscPR in bowel endometriosis. DESIGN: Retrospective analysis. S…

BackgroundBlastocyst formation represents an essential requirement for subsequent implantation. Successful embryo implantation depends on adequate endometrial receptivity and appropriate embryo-maternal communication. Uterus-derived extrace…

OBJECTIVE: The aim of this study was to compare surgical outcomes of two laparoscopic techniques for bowel endometriosis and determine the optimal laparoscopic segmental resection technique with mesentery preservation. MATERIALS AND METHOD…

OBJECTIVES: Parthenolide (PTL) has significant anti-inflammatory and immunomodulatory effects, but its regulatory mechanisms in endometriosis (EMs) remain unclear. This study aimed to systematically evaluate the effects of PTL on cellular m…

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…

BackgroundOvarian maldescent is a rare congenital anomaly in which one or both ovaries are positioned abnormally above the pelvic brim. However, the potential relationship between ovarian maldescent and infertility remains poorly understood…

As a heterogeneous disease, endometriosis is associated with diagnostic delay. Delayed diagnosis, physical discomfort, hormone therapy, and inconvenience in daily life and work all contribute to a decreased quality of life for endometriosis…

ObjectiveThe causative role of gut microbiota in pancreatitis remains unknown. This study aimed to investigate potential causal associations between gut microbiota and pancreatitis, using bidirectional Mendelian randomization (MR) analysis.…

Vulvar lichen sclerosus (VLS) is a chronic skin condition affecting the vulva, causing significant discomfort, but its etiology in prepubertal girls remains poorly understood. VLS presents with itching, irritation, and pain. Recent studies …

Study questionWhat are the impacts of different male infertility factors on embryological, cumulative pregnancy and neonatal outcomes of IVF/ICSI cycles?Summary answerSome severe male infertility factors, i.e. severe oligoasthenozoospermia …

OBJECTIVES: To assess the potential impact of years of education, which serves as a measure of socioeconomic inequality, on the occurrence of endometriosis, and to quantify the potential influence of modifiable factors as mediators. METHOD…

BackgroundFor poor ovarian response patients, obtaining higher number of transferable and high-quality embryos is crucial and progestin-primed ovarian stimulation protocol is becoming widespread and constantly improving in this population. …

ObjectiveTo evaluate the pregnancy and perinatal outcomes of different phenotypes of polycystic ovary syndrome (PCOS) patients during the frozen embryo transfer (FET) cycles. Additionally, to analyze the T cell balance in the endometrium of…

BackgroundThe risk of ectopic pregnancy (EP) is known to increase with assisted reproductive technology (ART), but the specific risk factors are unclear.MethodsWe screened 6872 cycles for clinical data that met our study's inclusion criteri…

BackgroundProgrammed protocols are most commonly chosen as endometrial preparation for women with polycystic ovarian syndrome (PCOS) undergoing frozen-thawed embryo transfer (FET) cycles. However, the efficacy of gonadotropin-releasing horm…

Endometriosis is a chronic inflammatory disorder characterized by presence of endometrial tissue outside the uterine cavity. Immunohistochemical analysis (IHC) revealed markedly elevated expression of IL6ST in endometrial tissue of patients…

BackgroundOverweight and obesity can induce an inflammatory milieu in the oocyte microenvironment and are closely associated with reduced assisted reproductive outcomes.ObjectiveHow are immune cells, cytokines and lipid profiles altered in …

Endometriosis (EMs) is a common gynecological disorder. According to the most widely recognized theory of retrograde menstruation, endometrial cells require completion of three key steps during ectopic implantation: adhesion, invasion, and …

ObjectiveTo assess the efficacy of preimplantation genetic testing for aneuploidies (PGT-A) compared to intracytoplasmic sperm injection (ICSI) alone in couples undergoing ICSI treatment because of severe male infertility.DesignMulticentre,…

While the blood urea nitrogen/albumin ratio (BAR) is recognized for its prognostic significance in various diseases, its association in acute pancreatitis (AP) remains uncertain. This research seeks to clarify the relationship between BAR a…

BackgroundPrimary Sjögren syndrome (pSS) is often related to adverse neonatal outcomes. But it's currently controversial whether pSS has an adverse effect on female fertility and clinical pregnancy condition. More importantly, it's unclear …

BackgroundWith the increasing incidence of obesity and the childbearing-age delay among women, a debate over obesity's impacts on pregnancy and neonatal outcomes becomes hot. The potential negative effects of obesity and aging on fertility …

BackgroundObesity poses a significant global health challenge, with profound implications for women's reproductive health. The relationship between ovarian reserve and body mass index (BMI) remains a subject of debate. While obesity is gene…

IntroductionPrevious studies have demonstrated that abnormal body mass index (BMI) is associated with adverse pregnancy outcomes in frozen-thawed embryo transfer cycles. However, the relationship between BMI and pregnancy and perinatal outc…