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Research questionIs a mixture of preconception serum lipids and lipophilic micronutrients associated with clinical pregnancy and live births?DesignIn this prospective cohort study, blood serum was collected on the day of oocyte retrieval fo…
ContextFatty acids (FAs) are important for reproductive processes, including steroidogenesis, though associations with fecundability, as measured by time to pregnancy (TTP), are unclear.ObjectiveTo investigate the relationship between preco…
PurposeFollicular redox balance is likely to be important for embryo quality during in vitro fertilization (IVF), and the anti-oxidative high desity lipoprotein (HDL) particle is the sole lipoprotein measured in follicular fluid (FF). There…
The importance of high-density lipoprotein (HDL) particle components to reproduction is increasingly recognized, including the constituent paraoxonase 1 (PON1). However, the reliability characteristics of PON1 enzymes in ovarian follicular …
BackgroundEvidence is growing that the equilibrium between reactive oxygen species and antioxidants plays a vital role in women's reproductive health.ObjectiveThe objective of this study was to evaluate variations in serum antioxidant conce…
ObjectiveTo assess the variability of follicular fluid (FF) high-density lipoprotein (HDL) particle components.DesignCross-sectional design with assessment using two-stage nested analysis of variance.SettingReproductive health center.Patien…
BackgroundOxidative stress has been associated with a variety of chronic diseases and reproductive disorders. Fruits and vegetables (F/V) may contribute to antioxidant vitamin and micronutrient levels and reduce oxidative stress.ObjectiveTo…
Trace exposures to the toxic metals mercury (Hg), cadmium (Cd) and lead (Pb) may threaten human reproductive health. The aim of this study is to generate biologically-plausible hypotheses concerning associations between Hg, Cd, and Pb and i…
Studies in both human and animal species have suggested that oxidative stress may be associated with health outcomes, including the risk of infertility in both males and females. Sex hormones have been shown to have antioxidant properties. …
PurposeTo investigate whether follicular fluid lipid-soluble micronutrients are associated with embryo morphology parameters during IVF.MethodsFollicle fluid and oocytes were obtained prospectively from 81 women. Embryo morphology parameter…
Little information is available on the intra-individual variability of oxidative stress biomarkers in healthy individuals and even less in the context of the menstrual cycle. The objective of this study was to characterize the analytical an…