Samartzis EP

No ORCID on file · 18 papers in corpus · active 2011-2025

Study types

  • article 7
  • review 5
  • other 3
  • meta-analysis 1

Condition tags

  • endometriosis 16
  • infertility 3
  • die_deep_infiltrating 1
  • adenomyosis 1
article 2025
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.114625

INTRODUCTION: Many women with endometriosis turn to digital sources for information. Meanwhile, large language models (LLMs) appear capable of offering health advice. This study aimed to evaluate the potential in answering endometriosis-rel…

other 2024
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2024.08.044

Endometriosis is a disease affecting approximately 10% of reproductive age women. Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) occurs in some endometriosis cases. Histone deacetylase 6 (HDAC-6)…

other 2023
Journal of reproductive immunology ·doi:10.1016/j.jri.2023.103795

G protein-coupled estrogen receptor (GPER) has been found to be an important key regulator in the homeostasis of sex hormone-dependent human cells. The aim of this study was to compare the expression of GPER, estrogen receptor alpha (ER-α),…

meta-analysis 2021
Journal of reproductive immunology ·doi:10.1016/j.jri.2021.103338

INTRODUCTION: Endometriosis is an inflammatory condition, affecting mainly women of reproductive age. Leptin is a regulator of food intake and energy expenditure, posing pleiotropic actions, and regulating immunity and fertility. The aim of…

review 2021
BMC women's health ·doi:10.1186/s12905-021-01545-5

BACKGROUND: Endometriosis, the presence of endometrial-like tissue outside the uterus, is a common clinical entity between women of reproductive age, with a prevalence of about 10%. Due to the variety of endometriosis-associated symptoms, a…

review 2020
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05445-1

BackgroundEndometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcinomas such as clear ce…

review 2020
Annals of translational medicine ·doi:10.21037/atm-20-3022a

Abstract: Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of reproductive age. It is defined by the presence of endometrial-like tissue in localizations outside of the uterine cavity. It often causes sym…

review 2019
Hormones (Athens, Greece) ·doi:10.1007/s42000-019-00166-w

BackgroundEndometriosis is one of the most common gynecological diseases of reproductive age, with a prevalence of 5-10% and grave consequences for quality of life and fertility. Vitamin D (vit D), a classic regulator of plasma calcium conc…

article 2019
Archives of gynecology and obstetrics ·doi:10.1007/s00404-019-05157-1

PurposeComparison of preoperative magnetic resonance imaging (MRI) with intraoperative findings in patients with deep infiltrating endometriosis (DIE) by means of the ENZIAN score.MethodsThis retrospective two-center study includes 63 patie…

2017
BMC cancer ·doi:10.1186/s12885-017-3054-6

BackgroundEndometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer …

article 2016
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1137094

Endometriosis, a painful disorder associated with infertility, is estimated to occur in approximately 7-10% of reproductive age women. Although endometriosis is considered as an estrogen-dependent disease, the role of estrogen metabolites v…

2014
Oncotarget ·doi:10.18632/oncotarget.2092

ARID1A mutations are observed in various tumors, including ovarian clear cell (OCCC) and endometrioid carcinomas, endometrial, and breast carcinomas. They commonly result in loss of ARID1A-protein expression and frequently co-occur with PI3…

review 2013
International journal of molecular sciences ·doi:10.3390/ijms140918824

Endometriosis is a common gynecological disease affecting 6%-10% of women of reproductive age and is characterized by the presence of endometrial-like tissue in localizations outside of the uterine cavity as, e.g., endometriotic ovarian cys…

article 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.05.008

ObjectiveTo investigate whether histone deacetylase inhibitors reduce the expression of the G-protein-coupled estrogen receptor (GPER) and whether the functional inhibition of GPER by the antagonist G-15 decreases the proliferation of endom…

other 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113488450

Class I histone deacetylases (HDACs-1-3) play an important role in steroid hormone-dependent gene expression and in modulating cell survival and proliferation. We analyzed their expression in a tissue microarray including 74 endometriosis s…

article 2012
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-10-30

BACKGROUND: The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from e…

article 2012
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2011.217

Mutations of the tumor-suppressor gene ARID1A result in the loss of protein expression of the BRG-associated factor 250a (BAF250a), a large subunit of transcription-regulating Human SWI/SNF complexes, which have an important role in the con…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.12.058

ObjectiveTo investigate whether the histone deacetylase (HDAC) inhibitor romidepsin down-regulates VEGF (vascular endothelial growth factor) gene expression and abrogates VEGF protein secretion in human epithelial endometriotic cells.Design…