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BackgroundHydrosalpinx is a recognized condition affecting the fallopian tubes, which decreases the embryo implantation rate and success in in vitro fertilization (IVF) outcomes. It can manifest detrimental effects through inflammatory cond…
Laparoscopy is the gold standard for diagnosing endometriosis; however, it is an invasive and costly method. Recent studies offer a non-invasive approach based on extracellular vesicle miRNA. Despite this, no consensus diagnostic biomarker …
BackgroundEctopic pregnancy (EP) is defined as embryo implantation in a location other than the uterine cavity.ObjectiveWe aimed to evaluate the expression of several genes, which may play a role in EP, in the ampulla region of fallopian tu…
ObjectiveDiminished ovarian reserve (DOR) is a challenging issue encountered during assisted reproductive technology. Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) belong to the transforming growth factor-…
BackgroundPremature ovarian failure (POF) is characterized by the loss of ovarian activity before the age of 40 years. Stem cell therapy has the capability to create a regenerative microenvironment and is a proposed treatment for POF-relate…
OBJECTIVE: promoter polymorphisms and susceptibly to endometriosis and its corolation with mRNA level. MATERIALS AND METHODS: were detected by sequencing. Quantitative polymerase chain reaction (Q-PCR) was carried out to determine MIF expre…
OBJECTIVE: Endometriosis is a common complex gynecological disorder that may result in infertility. Macrophage migration inhibitory factor (MIF) is a key pro-inflammatory cytokine that is overexpressed in endometriosis tissues. However, hit…