Young Min Choi

BACKGROUND: The purpose of this study was to investigate the potential association of the C627T polymorphism in the interleukin-2 receptor beta gene (IL-2R beta) with the risk of endometriosis in Korean women. METHODS: Two hundred and thir…

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue outside the uterus, causing diverse diseases, including infertility, pelvic pain, dysmenorrhea, and constipation. While there is a growing body of evidence that gene…

BACKGROUND: This study was performed to investigate whether specific haplotypes and several single nucleotide polymorphisms in the promoter region of the tumor necrosis factor (TNF)-alpha gene are associated with the risk of advanced stage …

Angiogenin, a potent inducer of angiogenesis, is expressed in human endometrium. This study was performed to compare the expression of angiogenin mRNA level in the eutopic endometrium from women with and without endometriosis. Thirty-two wo…

OBJECTIVE: To analyze the influence of postoperative GnRH agonist treatment on disease recurrence after conservative laparoscopic surgery for ovarian endometriomas according to duration of the treatment. DESIGN: Retrospective cohort study.…

OBJECTIVES: To investigate the associations between endometriosis and the G(-2518)A polymorphism of monocyte chemotactic protein-1 (MCP-1), and serum and peritoneal fluid MCP-1 levels in Korean women. STUDY DESIGN: The G(-2518)A polymorphi…

The aim of present study was to evaluate the relationship between endometriosis and polymorphisms in the endostatin and vascular endothelial growth factor (VEGF) genes, and their levels in serum in a Korean population. Serum endostatin leve…

BACKGROUND: This study was performed to determine whether genetic polymorphisms of aryl hydrocarbon receptor repressor (AhRR), glutathione-S-transferase M1 (GSTM1) and glutathione-S-transferase T1 (GSTT1) are associated with susceptibility …

OBJECTIVE: To investigate whether the +1730 G/A polymorphism of the estrogen receptor beta (ER-beta) gene is associated with the risk of endometriosis in a Korean population. DESIGN: Case-control study. SETTING: University Department of O…

This study was performed to investigate the association between FSH receptor (FSHR) gene polymorphism at position 680 and the outcomes of controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) in K…

BACKGROUND: Endometriosis is considered a frequent, benign disease with the ability to undergo neoplastic processes. The aim of this study was to evaluate the limitless replication potential of the endometrium in patients with endometriosis…

Objective: To explore the association of the interleukin-10 (IL-10) gene -592 promoter polymorphism with endometriosis in a Korean population. Methods: This study comprised 254 women with surgically or histologically diagnosed endometriosis…

The aim of the present study was to evaluate the clinical efficacy of half-dose (50 mug) and further reduced dose (33 or 25 mug) gonadotropin-releasing hormone agonist (GnRH-a; triptorelin) long protocols for multifollicular ovarian stimula…

Objective: To explore the association of the CYP 1A1 gene polymorphism with the risk of endometriosis in a Korean population. Design: Case-control study Methods: Two-hundred fifty two Korean women with surgically or histologically diagnosed…

The present study was designed to explore the association between estrogen receptor-alpha gene polymorphism and the risk of endometriosis by investigating the frequency of PvuII, XbaI, and thymine-adenine (TA) repeat polymorphisms in patien…

OBJECTIVE: To investigate the effects of nitric oxide on endometrial cell proliferation and the effects of peritoneal fluid from women with and without endometriosis on the production of nitric oxide and upon the nature of nitric oxide-indu…

BACKGROUND: The aetiological factors of endometriosis still remain poorly understood. While there is growing evidence that genetic and immunological factors play important roles in the pathogenesis of the disease, HLA-DRB1 alleles have been…

BACKGROUND: Vascular endothelial growth factor (VEGF) is known to play a pivotal role in the development of endometriosis. This study was performed to investigate whether the VEGF gene 5'-untranslated region polymorphism is associated with …

OBJECTIVE: To evaluate the relationship between the alpha 2-Heremans Schmidt glycoprotein (AHSG) gene polymorphism and endometriosis. DESIGN: Case-control study. SETTING: Department of Obstetrics and Gynecology, Seoul National University …

목적 : 한국 여성에서 에스트로겐 수용체 유전자의 dinucleotide repeat 다형성과 자궁내막증의 연관성에 대하여 조사하고자 하였다. 연구 방법 : 수술 소견 또는 조직검사상 자궁내막증으로 진단된 156명의 여성을 환자군으로 하였으며, 복강경 검사 또는 개복술을 시행하였으나 자궁내막증의 증거를 발견할 수 없었던 137명을 대조군으로 하였다. 이들에서 에스트로겐 수용체 유전자의 dinucleotide repeat 다형…

Objective : To explore the association of p53 codon 72 polymorphism with endometriosis. Methods : Two hundred seventy-one women with surgically or histologically diagnosed edometriosis of stage I-IV, and 219 patients with no evidence of end…