Olivares CN

No ORCID on file · 9 papers in corpus · active 2011-2022

Study types

  • article 9

Condition tags

  • endometriosis 9
  • infertility 3
article 2022
Effects of pharmacological inhibition of hyaluronic acid synthesis on experimental endometriosis
European journal of clinical investigation ·doi:10.1111/eci.13899

BACKGROUND: Dysregulated hyaluronic acid (HA) metabolism has been shown to be implicated in several pathologies including endometriosis. 4-Methylumbelliferone (4MU) is an HA synthesis inhibitor with proven antitumour activity. In this study…

article 2021
Effect of urolithins A and B on ectopic endometrial growth in a murine model of endometriosis
Food & function ·doi:10.1039/d1fo01702k

< 0.01, respectively). These results are promising and reveal that urolithins A and B, separately, have a beneficial effect on the overall endometriotic growth without affecting the body weight or estrous cycle.

article 2018
Active compounds present inRosmarinus officinalis leaves andScutellaria baicalensis root evaluated as new therapeutic agents for endometriosis
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2018.09.018

Research questionCan carnosic acid, (CA) rosmarinic acid (RA) and wogonin (WG) inhibit the growth of cultured human endometrial stromal cells and endometriotic-like lesions induced in a BALB/c model of endometriosis?DesignPrimary stromal ce…

article 2016
Inhibition of Hyaluronic Acid Synthesis Suppresses Angiogenesis in Developing Endometriotic Lesions
PloS one ·doi:10.1371/journal.pone.0152302

BACKGROUND: The development and long-term survival of endometriotic lesions is crucially dependent on an adequate vascularization. Hyaluronic acid (HA) through its receptor CD44 has been described to be involved in the process of angiogenes…

article 2015
Interplay between Endometriosis and Pregnancy in a Mouse Model
PloS one ·doi:10.1371/journal.pone.0124900

OBJECTIVES: To evaluate the effect of endometriosis on fertility and the levels of the IL-2 and IFN-γ in the peritoneal fluid in a mouse model; to evaluate the effect of pregnancy on endometriotic lesion growth, apoptosis and cell prolifera…

article 2014
Targeting galectin‐1‐induced angiogenesis mitigates the severity of endometriosis
The Journal of Pathology ·doi:10.1002/path.4397

Endometriosis is characterized by the presence of endometrial tissue outside the uterus that causes severe pelvic pain and infertility in women of reproductive age. Although not completely understood, the pathophysiology of the disease invo…

article 2012
Anastrozole and celecoxib for endometriosis treatment, good to keep them apart?
Reproduction (Cambridge, England) ·doi:10.1530/rep-12-0386

Endometriosis is a benign gynecological disease. Cyclooxygenase-2 (COX-2) and aromatase proteins have been shown to be overexpressed in eutopic endometrium from women suffering from this disease compared to disease-free women. Furthermore, …

article 2012
Natural therapies assessment for the treatment of endometriosis
Human Reproduction ·doi:10.1093/humrep/des369

STUDY QUESTION: Can resveratrol and epigallocatechin-3-gallate (EGCG) inhibit the growth and survival of endometriotic-like lesions in vivo in a BALB/c model of endometriosis, and in vitro in primary cultures of human endometrial epithelial…

article 2011
Effect of Vascular Endothelial Growth Factor Inhibition on Endometrial Implant Development in a Murine Model of Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110395406

The main factor involved in neovascularization of ectopic endometrial tissue in endometriosis is the vascular endothelial growth factor (VEGF), which is produced both by the endometrial implant and by peritoneal macrophages. On the other ha…