Seang Lin Tan

Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. …

Background: Despite significant advances in assisted reproductive technology (ART), disparities in clinical outcomes persist. While patient-related factors are well-studied, the role of partner ethnicity remains understudied. We hypothesize…

BackgroundThis study aims to determine whether pre or post-processing semen parameters obtained during intrauterine insemination (IUI) predict pregnancy when controlling for confounding effects.Materials and methodsA prospective cohort stud…

OBJECTIVE: To determine whether 2 months of pretreatment with 5 mg of letrozole daily plus leuprolide acetate at 3.75 mg monthly in women with laparoscopically confirmed American Society of Reproductive Medicine stage I-II endometriosis imp…

ObjectiveTo compare the influence of dual suppression with the use of GnRH agonist plus aromatase inhibitor compared with suppression with the use of GnRH agonist alone or no suppression at all in patients with idiopathic recurrent implanta…

Research questionDoes the addition of an aromatase inhibitor improve IVF outcomes in women with endometriomas when pretreating them with gonadotrophin-releasing hormone agonists?DesignRetrospective two-centre cohort study involving 126 wome…

Intrauterine devices (IUDs) have been widely used to prevent pregnancies with great efficacy during decades. It has been demonstrated that IUD alters the endometrial gene expression, but there is no scientific data about how copper, a metal…

Objective: This study was undertaken to evaluate the effects of different stages of endometriosis on the outcome of treatment in an in vitro fertilization (IVF) program. Methods: This was a retrospective, matched case-control study in an ac…

ObjectiveTo compare complication rates and pain scores after oocyte pickup (OPU) in in vitro maturation (IVM) and IVF cycles.DesignRetrospective cohort study.SettingUniversity-affiliated ART center.Patient(s)One hundred eighty-eight IVM and…

ObjectiveTo evaluate the effects of ovarian endometrioma on the number of oocytes retrieved for IVF.DesignRetrospective case control study.SettingUniversity-based tertiary medical center.Patient(s)We studied 81 women with unilateral endomet…

ObjectiveTo report a new indication for fertility preservation.DesignCase report.SettingAcademic teaching hospital.Patient(s)A 25-year-old nulliparous woman with severe and symptomatic endometriosis and low antral follicular count.Intervent…

ObjectiveThis study was undertaken to evaluate the effects of different stages of endometriosis on the outcome of treatment in an in vitro fertilization (IVF) program.MethodsThis was a retrospective, matched case-control study in an academi…

OBJECTIVES: To assess the effect of short-term (2-3 weeks) pituitary suppression and controlled ovarian stimulation on ovarian and uterine artery Doppler measurements during the in vitro fertilization (IVF) treatment cycle and to compare th…

ObjectiveTo compare the incidence and severity of local side effects of urinary-derived gonadotropins administered s.c. and i.m..DesignProspective randomized study of women undergoing IVF treatment.SettingTertiary referral center for assist…

A total of 96 women undergoing in vitro fertilization (IVF) treatment were studied on the day of human chorionic gonadotropin (hCG) administration by transvaginal ultrasonography with color and pulsed Doppler ultrasound. We assessed endomet…

ObjectiveTo compare the midluteal uterine artery impedance to blood flow as measured by the pulsatility index in women with different causes of infertility with that of women with normal fertility and to correlate this with endometrial thic…