Comparison of complication rates and pain scores after transvaginal ultrasound–guided oocyte pickup procedures for in vitro maturation and in vitro fertilization cycles

Ayşe Seyhan; Barış Ata; Weon‐Young Son; Michael H. Dahan; Seang Lin Tan

doi:10.1016/j.fertnstert.2013.12.011

Comparison of complication rates and pain scores after transvaginal ultrasound–guided oocyte pickup procedures for in vitro maturation and in vitro fertilization cycles

Ayşe Seyhan, Barış Ata, Weon‐Young Son, Michael H. Dahan, Seang Lin Tan

In: Fertility and Sterility · 2014 · vol. 101(3) , pp. 705–709 · doi:10.1016/j.fertnstert.2013.12.011 · PMID:24424363 · W1977748286

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This study compared complication rates and pain scores between transvaginal ultrasound-guided oocyte pickup for in vitro maturation and in vitro fertilization cycles.

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Abstract

ObjectiveTo compare complication rates and pain scores after oocyte pickup (OPU) in in vitro maturation (IVM) and IVF cycles.DesignRetrospective cohort study.SettingUniversity-affiliated ART center.Patient(s)One hundred eighty-eight IVM and 188 IVF OPUs.Intervention(s)IVM OPUs were done using a 19-gauge single-lumen needle, and IVF OPUs were done using a 17-gauge single- or 16-gauge double-lumen needles.Main outcome measure(s)Duration of OPU, complication rates, and pain scores during the OPU procedure.Result(s)IVM OPU took significantly more time than IVF OPU (22 vs. 15 minutes). Two women in the IVM and four in the IVF group experienced bleeding from the vaginal wall or ovary. None of them required hospitalization, transfusion, or an operative intervention. One patient in each group had pelvic infection. Severe post-OPU abdominal pain occurred in one patient in the IVM group and five patients in the IVF group. No differences were found between pain scores in the IVF and IVM groups (3.4 vs. 3.8).Conclusion(s)Although IVM OPU requires more punctures per ovary, it is well tolerated and does not seem to be associated with a higher complication rate than IVF OPU.

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[1] A review of complications following transvaginal oocyte retrieval for in-vitro fertilization 2004

[2] Perioperative and post-operative complications of transvaginal ultrasound-guided oocyte retrieval: prospective study of >1000 oocyte retrievals 2006

[3] Term delivery following tuboovarian abscess after in vitro fertilization and embryo transfer 2013