Edgardo Somigliana

No ORCID on file · 332 papers in corpus · active 1995-2026

Study types

  • article 153
  • review 81
  • other 49
  • letter 16
  • meta-analysis 11

Condition tags

  • endometriosis 291
  • infertility 53
  • endometrioma 38
  • chronic_pelvic_pain 29
  • adenomyosis 28
  • dyspareunia 17
  • dysmenorrhea 16
  • bowel_endometriosis 15
  • die_deep_infiltrating 8
  • bladder_endometriosis 6
article 2008
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2007.11.010

ObjectiveThe purpose of this study was to compare the postoperative risk of endometrioma recurrence in women using oral contraception and in those undergoing simple observation.Study designAfter laparoscopic excision of ovarian endometrioti…

article 2008
·doi:10.1016/j.ajog.2008.05.037
article 2008
Human Reproduction ·doi:10.1093/humrep/den379

Laparoscopic treatment for endometriosis-associated infertility is gaining widespread popularity supported mostly by uncontrolled studies, but the purported benefit of surgery may be overvalued. We have therefore analysed the best available…

case-report 2008
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2007.09.004

A 25-year-old woman with unoperated deep endometriosis of the uterosacral ligament suddenly experienced severe abdominal pain, hematuria, hemoperitoneum, and intrauterine death at 31 weeks' gestation. Surgical intervention revealed active h…

review 2007
Human Reproduction ·doi:10.1093/humrep/dem224

BACKGROUND: If the menstrual reflux or implantation theory of endometriosis is true, refluxed endometrial cells could reach the right hypochondrium transported by the clockwise peritoneal fluid current and would implant more easily on the r…

article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.180

ObjectiveTo establish whether causality versus biases may explain the association of endometriosis and ovarian cancer.DesignWe employ the nine criteria proposed by Austin Bradford Hill, which still stand as foundation milestones for causal …

other 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.090

OBJECTIVE: It has been hypothesized that bladder endometriotic nodules are an independent form of endometriosis that should be considered a distinct clinical entity. If this is true, the frequency of nonvesical endometriotic lesions in affe…

article 2007
·doi:10.1016/j.fertnstert.2007.07.736
article 2007
·doi:10.1586/17474108.2.6.791

Endometriosis is a multifactorial disease that affects 6–10% of women of reproductive age. Epidemiological studies indicate that it is a polygenic disorder, with recurrence risks in first-degree relatives of approximately 2–9%. Thus, the cu…

review 2007
Frontiers in bioscience : a journal and virtual library ·doi:10.2741/2308

Family and twin studies have shown that heritability accounts for endometriosis development to an extent similar to other complex genetic diseases. Both linkage analysis and association studies have been performed to identify genetic determ…

article 2007
Women's health (London, England) ·doi:10.2217/17455057.3.2.207

Endometriosis-associated symptomatology can be safely and effectively treated with intrauterine-released progestin, which is associated with fewer adverse effects than other therapeutic options and may be used on a long-term basis. We have …

article 2007
Human Reproduction ·doi:10.1093/humrep/dem341

BACKGROUND: Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis potentially contributing to the pathogenesis of endometriosis. The aim of this study was to investigate the potential association between the single …

other 2007
Human Reproduction ·doi:10.1093/humrep/dem142

BACKGROUND: An immune-mediated defect in recognition and elimination of endometrial fragments refluxed in the peritoneal cavity has been hypothesized to play a crucial role in endometriosis development. Since vitamin D is an effective modul…

review 2006
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2006.01.017

Epidemiological studies of adenomyosis are difficult to interpret because the diagnostic criteria vary so widely that the disease may be easily over-diagnosed. This would severely hamper any attempt to define incidence and prevalence of the…

review 2006
Gynecologic oncology ·doi:10.1016/j.ygyno.2005.11.033

ObjectiveThis review was aimed to critically evaluate observational, cohort, and case-control studies performed so far in order to assess the association between endometriosis and malignant diseases. Based on the observations herein present…

other 2006
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2006.03.064

OBJECTIVE: This study was undertaken to determine the frequency of postsurgical ovarian failure in patients undergoing laparoscopic excision of bilateral endometriomas. STUDY DESIGN: Patients who had been operated on for bilateral ovarian …

article 2006
Minerva ginecologica

We performed a MEDLINE and EMBASE search to identify all studies published in the English language literature on the use of progestogens for the treatment of endometriosis. The aim of our review was to clarify the biological rationale for t…

article 2006
·doi:10.1016/j.ajog.2006.02.006
article 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.12.034

ObjectiveTo clarify whether the presence of ovarian endometriomas is associated with a reduced responsiveness to ovarian hyperstimulation.DesignObservational study.SettingUniversity teaching hospital.Patient(s)Women selected for in vitro fe…

article 2005
161
·doi:10.1016/j.jmig.2005.07.160
article 2005
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2005.05.056

ObjectiveRetrospective studies suggest that laparoscopic excision of endometriomas is associated with a reduced responsiveness to ovarian hyperstimulation. In this study, we prospectively evaluated ovarian response to hyperstimulation in wo…

review 2005
Human reproduction update ·doi:10.1093/humupd/dmi037

Although population-based studies have unequivocally reported an increased risk of ovarian cancer in women with endometriosis, the biological evidence supporting the idea of endometriosis as a preneoplastic condition is scanty and not well …

other 2005
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2005.06.006

STUDY OBJECTIVE: To evaluate damage to ovarian reserve following laparoscopic cystectomy of benign ovarian cysts. DESIGN: Prospective study (Canadian Task Force classification II-3). SETTING: Tertiary gynecologic endoscopic unit at a univ…

review 2005
Human reproduction update ·doi:10.1093/humupd/dmi035

The laparoscopic excision of ovarian endometriomas appears to increase the chances of spontaneous conception, but the value of this treatment in women selected for IVF-ICSI cycles is debated. Studies recruiting women with unilateral disease…

review 2005
Current opinion in obstetrics & gynecology ·doi:10.1097/01.gco.0000175353.03061.7f

PURPOSE OF REVIEW: The aim of this article is to evaluate the biological rationale for the use of an intrauterine device releasing 20 mug/day of levonorgestrel in women with endometriosis, and to assess its efficacy in relieving pelvic pain…