Edgardo Somigliana
No ORCID on file
· 332 papers in corpus
· active 1995-2026
Study types
- article 153
- review 81
- other 49
- letter 16
- meta-analysis 11
Condition tags
- endometriosis 291
- infertility 53
- endometrioma 38
- chronic_pelvic_pain 29
- adenomyosis 28
- dyspareunia 17
- dysmenorrhea 16
- bowel_endometriosis 15
- die_deep_infiltrating 8
- bladder_endometriosis 6
Top journals
Frequent coauthors
- Paolo Vercellini 201
- Paola Viganò 193
- Somigliana E 93
- Laura Benaglia 85
- Vercellini P 64
- Luigi Fedele 62
- Massimo Candiani 45
- Benaglia L 43
- Laura Buggio 41
- Michele Vignali 41
article
2005
An autoimmune etiology has been suggested for endometriosis mostly on the basis of an increased prevalence of autoimmune diseases in affected women. Cytotoxic T lymphocyte antigen (CTLA) 4 gene is recognized as a primary determinant for aut…
article
2004
Endometriosis is a benign gynaecologic disease that is associated with a certain risk for malignant degeneration. The disease has a genetic background, but the locations of possible genomic aberrations are still poorly clarified. In this co…
article
2004
ObjectiveA genetic variation in the androgen receptor (AR) has been associated with the risk of developing endometriosis. The AR gene is located on the X chromosome and contains a highly polymorphic trinucleotide repeat (cytosine, adenine, …
review
2004
Estimates of the frequency of endometriosis vary widely. Based on the few reliable data, the prevalence of the condition can reasonably be assumed to be around 10%. Although no consistent information is available on the incidence of the dis…
article
2004
Summary objective Endometriosis is a steroid‐dependent disease with a particular genetic background, but the locations of possible genomic aberrations are still poorly clarified. We have investigated the potential association between endome…
other
2004
BACKGROUND: Recent studies have proposed the measurement of CA 19-9 and IL-6 as an alternative to CA 125 as markers for endometriosis. This study was performed in order to verify the clinical value of serum CA 125, CA 19-9 and IL-6 levels, …
article
2003
article
2003
BACKGROUND: It has been suggested recently that deep endometriosis and the other forms of the disease do not share a common pathogenetic mechanism. In this study, we hypothesize that, if this is true, deep peritoneal endometriosis and the o…
article
2003
BACKGROUND: Residual ovarian function after laparoscopic excision of endometriotic ovarian cysts is a major and still unsolved topic. Ultrasonographic evaluation of ovarian response to ovulation stimulation represents a simple yet poorly em…
erratum
2003
article
2003
Endometriosis is a gynaecological disease with a certain genetic background, but the locations of possible genomic aberrations are still poorly clarified. Intercellular adhesion molecule-1 (ICAM-1), which is a surface glycoprotein that prom…
review
2003
We performed a MEDLINE and EMBASE search to identify all studies published in the last decade in the English language literature on the use of progestogens for the treatment of endometriosis. Our aim was to clarify the biological rationale …
article
2003
Surgery is still the first line of therapy for endometriosis. At present, medical therapy is mostly indicated for treatment and prevention of recurrences. Current pharmacological regimens induce a hypoestrogenic state; this effect tends, on…
article
2002
review
2002
ObjectiveTo discuss current ideas about therapy for endometriosis derived from new observations generated by using molecular biology techniques and in vivo animal models of disease.Method(s)The MEDLINE database was reviewed for English-lang…
article
2002
Symptomatic women with stage III to IV endometriosis today are most often managed by conservative laparoscopic surgery, but recurrences continue to occur. Roughly one in five patients will have further disease within 5 years after complete …
article
2002
letter
2002
It has been recently reported that serum concentrations of the adipocyte-derived hormone leptin are increased in patients affected by endometriosis. On the basis of these findings, the present study was undertaken to evaluate whether the pr…
other
2002
OBJECTIVE: To investigate the hypothesis that soluble intercellular adhesions molecule-1 (sICAM-1) may be used as a new serum marker of endometriosis. DESIGN: Prospective cohort study. SETTING: An academic department specializing in gynec…
article
2001
Follicular fluid from women with endometriosis has been shown to induce a higher endometrial cell proliferation than that derived from women without the disease. To elucidate this issue further, the aims of the present study were to compare…
letter
2001
other
2001
BACKGROUND: It is still unclear whether the immunologic perturbation observed in women with endometriosis represents an intrinsic defect of the immune system or it is consequent to the presence of endometrium in ectopic sites. The present s…
article
2001
article
2001
BACKGROUND: In order to decrease endometriosis recurrence after surgical therapy, it has been proposed to use a post-surgical oestrogen-lowering medical treatment. Results from previous trials on this topic are contradictory. METHODS: A tot…
article
2001
ObjectiveTo test the possibility of using transgenic knockout mice in the study of endometriosis and to investigate specific immunologic aspects of the disease.DesignExperimental blinded study.SettingAcademic research center.Animal(s)Thirty…