Edgardo Somigliana

No ORCID on file · 332 papers in corpus · active 1995-2026

Study types

  • article 153
  • review 81
  • other 49
  • letter 16
  • meta-analysis 11

Condition tags

  • endometriosis 291
  • infertility 53
  • endometrioma 38
  • chronic_pelvic_pain 29
  • adenomyosis 28
  • dyspareunia 17
  • dysmenorrhea 16
  • bowel_endometriosis 15
  • die_deep_infiltrating 8
  • bladder_endometriosis 6
article 2011
Gynecologic and obstetric investigation ·doi:10.1159/000323531

BACKGROUND/AIMS: Perinatal environmental exposure may affect fetal development and reprogram the developing organism for adult-onset disease. In this case-control study, we aimed at assessing this pathogenetic model in endometriosis. METHOD…

article 2011
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2011.01.053

ObjectiveCumulative evidence supports the view that ovarian endometriomas originate from ovulatory events and that the ovarian reserve is reduced following surgery. On these bases, we have hypothesized that the risk of recurrence may be rel…

article 2011
·doi:10.1093/humrep/der087

intake.It is for this reason that accurate information about the duration of post-operative hormonal treatment in each patient should be mandatory in all prospective or retrospective studies that focus on the surgical management of endometr…

review 2011
Placenta ·doi:10.1016/j.placenta.2011.06.011

The precise relationship between endometriosis and infertility is debated. Surgery is considered to play a role within the framework of the therapeutic options to cure infertile women with the disease even though its effectiveness is genera…

article 2011
Human Reproduction ·doi:10.1093/humrep/der211

Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian cancer. Most serous cancers appear to originate from precursor lesions at the fimbriated tubal end, whereas most endometrioid and clear cell can…

article 2011
Human Reproduction ·doi:10.1093/humrep/der097

BACKGROUND: There is a growing consensus that ovarian reserve is reduced after surgical excision of ovarian endometriomas. However, it remains to be fully clarified whether this damage precedes or follows surgery. In order to further elucid…

article 2010
Gynecologic and obstetric investigation ·doi:10.1159/000291809

Recent evidence suggested that periovulatory treatment with an immunomodulatory agent such as verapamil might be an effective alternative to conventional treatment for endometriosis-associated subfertility. In particular, it has been report…

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.01.071

OBJECTIVE: To evaluate the efficacy and tolerability of a contraceptive vaginal ring and transdermal patch in the treatment of endometriosis-associated pain. DESIGN: Patient preference cohort study. SETTING: Academic center. PATIENT(S): …

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.10.014

OBJECTIVE: To evaluate differences in endometrial stromal cell (ESC) migration between patients with and without endometriosis. DESIGN: Differences in ESC migration, cellular morphology, and cytoskeletal-actin dynamics were evaluated in re…

article 2010
Human Reproduction ·doi:10.1093/humrep/dep453

BACKGROUND: There is limited but interesting evidence suggesting that endometriosis may be associated with specific pigmentary traits and sun habits. In this case-control study, we aimed to further clarify this point. MATERIALS AND METHODS:…

article 2010
Human Reproduction ·doi:10.1093/humrep/deq141

Laparoscopy is the gold standard for the diagnosis of endometriosis. Although some forms of the disease, such as ovarian endometriomas or deep infiltrating lesions, can now be reliably diagnosed using non-invasive instruments, adhesions and…

review 2010
Human reproduction update ·doi:10.1093/humupd/dmq042

BACKGROUND: Combined oral contraceptives (OCs) inhibit ovulation, substantially reduce the volume of menstrual flow and may hypothetically interfere with implantation of refluxed endometrial cells. The aim of this review is to establish if …

article 2010
·doi:10.5301/je.2010.595

Although documented rates of endometriosis in adolescent patients undergoing laparoscopy for chronic pelvic pain range from about 25% to 45%, adolescent endometriosis has received limited attention in terms of research activity and follow-u…

article 2010
·doi:10.1177/228402651000200104

Although documented rates of endometriosis in adolescent patients undergoing laparoscopy for chronic pelvic pain range from about 25% to 45%, adolescent endometriosis has received limited attention in terms of research activity and follow-u…

article 2010
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2010.04.018

Prevention of the recurrence of post-operative endometriosis is crucial for future fertility. The incidence of disease relapse can be influenced by major demographic changes and by the use of long-term adjuvant medical treatment. Decrease i…

review 2010
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110382921

Women with endometriosis have a substantial increase in risk of deep dyspareunia with respect to the general female population of corresponding age. This symptom has personal and intimate implications, including unfavorable emotional impact…

book-chapter 2010
·doi:10.5005/jp/books/11032_23
article 2010
Human Reproduction ·doi:10.1093/humrep/dep464

BACKGROUND: There is growing and consistent evidence showing that ovarian reserve is affected following surgical excision of ovarian endometriomas. Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ov…

article 2010
·doi:10.1093/humrep/deq251
article 2010
·doi:10.1093/humrep/de.25.s1.5
article 2010
Human Reproduction ·doi:10.1093/humrep/deq302

Conservative surgical treatment for symptomatic endometriosis is frequently associated with only partial relief of pelvic pain or its recurrence. Therefore, medical therapy constitutes an important alternative or complement to surgery. Howe…

article 2009
·doi:10.5301/je.2009.2828
article 2009
·doi:10.1177/228402650900100102

The pathogenesis of some forms of endometriosis is still controversial. Different research approaches have been used to clarify this issue and an intense debate has derived over the years among scientists. This paper presents and discusses …

article 2009
BJOG: An International Journal of Obstetrics & Gynaecology ·doi:10.1111/j.1471-0528.2008.02055.x

OBJECTIVE: To detect a direct transition from a haemorrhagic corpus luteum to an endometriotic cyst by serial transvaginal ultrasonographic scans. DESIGN: Prospective observational study. SETTING: An academic tertiary care and referral cent…

review 2009
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590802549858

Chronic pelvic pain (CPP), defined as non-cyclic pain of 6 or more months, is a frequent disorder that may negatively affect health-related quality of life. In women several causes are recognised, although in a not negligible proportion of …