Reply: Oral contraceptives and the endometriosis domino effect

In: Human Reproduction · 2011 · vol. 26(6) , pp. 1601–1602 · doi:10.1093/humrep/der087 · W2115216453
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This letter argues that future endometriosis studies must document post-operative hormonal treatment duration to accurately assess recurrence rates and inform surgical management decisions.

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Abstract

intake.It is for this reason that accurate information about the duration of post-operative hormonal treatment in each patient should be mandatory in all prospective or retrospective studies that focus on the surgical management of endometriosis.This would allow for the likelihood of post-operative recurrences to be estimated from two distinct survival curves one with a starting point at the time of surgery, and the other at the end of post-operative medical therapy.The acceptance by surgeons that medical treatment should systematically be prescribed in order to suppress the development of small residual foci responsible for recurrences would allow further questioning as to whether extensive surgery and compulsive carcinologic resection of all endometriosis lesions is still mandatory, particularly in cases with a high risk of unfavourable post-operative functional outcomes (Roman et al., 2010).We are some way from answering this question, but contributions such as those of Vercellini et al. lead me to believe that we are on the right track.

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endometriosis

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