Jinghe Lang

OBJECTIVE: To establish the diagnostic model for endometriosis by screening the plasma biomarkers of endometriosis using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS)coupled with bioinformatics…

Thrombospondin-1 messenger RNA and protein levels in cultured human endometrial stromal cells (ESCs) treated with 17-beta estradiol (10 nM) were reduced by 47.6% (+/-6.5% SD; P < 0.05) and 49.0% (+/-8.6%; P < 0.05) compared with untreated c…

OBJECTIVE: To analyze the clinical presentation of perineal endometriosis and evaluate its treatment. METHODS: Clinical data were analyzed from the records of 36 patients with perineal endometriosis who were operated on between 1983 and 20…

OBJECTIVE: To investigate the relationship between degree of endometrioma adhesions and clinical feature, surgical treatment and postoperative recurrence. METHODS: From Jan 2003 to Mar 2008, 662 patients with endometrioma undergoing laparo…

OBJECTIVE: To set up the proteomic protein profiling of adenomyotic tissue and normal uterine muscle and identify the abnormally expressed proteins in adenomyotic tissue. METHODS: Samples of adenomyotic tissue (adenomyosis group) and age-m…

BACKGROUND: Annexin-1 was identified as an endometriosis-related protein by comparative proteomics in previous study. As an endogenous anti-inflammatory mediator, Annexin-1 has been shown to regulate the immune response, cell proliferation …

OBJECTIVE: To investigate the clinical features and management of ureteral endometriosis. METHODS: Patients surgically and histologically diagnosed as ureteral endometriosis from January 2001 to January 2007 in Peking Union Medical College…

To investigate the diagnosis and treatment of perineal endometriosis.The clinical date of 30 patients with perineal endometriosis, aged 32.3 (23 approximately 44), who were admitted 1983 - 2006, operated on, and followed up for 0.5 approxim…

OBJECTIVE: To identify the differently expressed proteins in adenomyotic tissue compared with normal uterine muscle. DESIGN: Retrospective, case-controlled study. SETTING: University-based Department of Obstetrics and Gynecology and Prote…

OBJECTIVE: To compare the clinical characteristics of three subcategories of laparoscopic hysterectomy: total laparoscopic hysterectomy (TLH) and two subcategories of laparoscopic-assisted vaginal hysterectomy (LAVH): LAVHs and LAVHb. METH…

In this prospective case-control study, we determined the role of surface-enhanced laser desorption and ionization time-of-flight mass spectrometry in the detection of histologically proven endometriosis. In the plasma of the group with end…

OBJECTIVE: To investigate the apoptosis-related mechanisms of levenorgestrel-releasing intrauterine system (LNG-IUS), oral medroxyprogesterone (MPA), and injective gonadotrophic hormone releasing hormone agonist (GnRHa) on eutopic endometri…

OBJECTIVE: To investigate the effects of progesterone and progestin on the expressions of regulated on activation, normal T cell expressed and secreted (RANTES) in eutopic endometrium from patients with endometriosis. METHODS: We collected…

Objective To investigate the effects of progestin and/or GnRHa on the expression of VEGFs in eutopic endometrium of women with endometriosis.Methods we collected the samples of endometrium from patients with endometriosis before operation, …

OBJECTIVE: To investigate the impact of danazol alginate microspheres used for uterine arterial embolization (UAE) on ovarian function and subsequent pregnancy using rabbit as a model. METHODS: A total of 32 female rabbits were divided int…

OBJECTIVE: To study the relationship between pain symptoms and the clinico-pathological features of pelvic endometriosis (EM). METHODS: One hundred thirty patients with laparoscopic diagnosis of EM were studied retrospectively and the rela…

OBJECTIVE: To establish the chick embryo chorioallantioc membrane (CAM) as a model for in vivo research on endometriosis. The model was used to investigate the mechanism of anti-vascular endothelial growth factor (VEGF) antibody for treatme…

Malignant change of endometriosis in a cesarean scar (CS) is rare. We report a case of carcinosarcoma arising from atypical endometriosis in a CS scar, which was successfully treated with complete excision of the lesion and repair of the ab…

OBJECTIVE: To investigate the clinical diagnosis, treatment and prevention of fallopian tube prolapse (FTP) after hysterectomy. METHODS: A total of 7949 patients received hysterectomy from 1983 to Aug 2005 in Peking Union Medical College H…

Objective To investigate the clinical characteristics of cases undergoing repeated resection in patients with abdominal wall endometriosis (AWE).Methods Retrospective analyses were performed in 101 patients with abdominal wall endometriosis…