Donnez J
No ORCID on file
· 189 papers in corpus
· active 1982-2025
Study types
- article 86
- review 44
- other 34
- letter 9
- editorial 5
Condition tags
- endometriosis 160
- infertility 27
- adenomyosis 26
- chronic_pelvic_pain 9
- dyspareunia 9
- endometrioma 8
- dysmenorrhea 7
- bowel_endometriosis 3
- bladder_endometriosis 1
Top journals
Frequent coauthors
review
2016
Endometriosis is a disorder associated with a general inflammatory response in the peritoneal cavity. Oxidative stress is a potential factor involved in the pathophysiology of this disease, and reactive oxygen species (ROS) are implicated i…
review
2016
INTRODUCTION: Endometriosis is a chronic estrogen-dependent inflammatory disease of unclear etiology that affects 15-20% of women of reproductive age. Efforts are now focusing on understanding new mechanisms involved in its physiopathology,…
2016
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses, pelvic pain, infertility, bulk symptoms and obstetric complications.Al…
article
2015
ObjectiveTo determine the implications of collective cell migration in the invasion phenomenon observed in deep endometriotic lesions induced in a baboon model.DesignStudy of morphology and collective cell migration markers in invasive and …
letter
2015
article
2014
ObjectiveTo evaluate the effects of endometriomas on the regulation of early follicular development.DesignHistologic analysis of prospectively collected biopsy samples.SettingResearch unit in a university hospital.Patient(s)Women <40 years …
2013
PurposeTo review 15 years of activities in ovarian tissue cryobanking from medical database files, including patient indications, histological evaluation and clinical characteristics.MethodsRetrospective longitudinal analysis of data from a…
article
2013
ObjectiveTo evaluate, in peritoneal, ovarian, and rectovaginal endometriotic lesions, expression of steroidogenic enzymes involved in the activation and inactivation of estrogens: 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1) and 2 (HSD…
2013
PurposeTo assess the safety of reimplantation of cryopreserved ovarian tissue from advanced-stage breast cancer patients.MethodsCryopreserved ovarian cortical fragments were obtained from 13 advanced-stage breast cancer patients aged 17-35 …
article
2013
ObjectiveTo study the occurrence of nerve fibers in deep nodular endometriotic lesions after nodules were induced in baboons and nerve fiber densities measured 6 months after the grafting procedure.DesignExperimental animal study.SettingAca…
letter
2013
review
2012
Deep endometriosis, defined as adenomyosis externa, mostly presents as a single nodule, larger than 1 cm in diameter, in the vesicouterine fold or close to the lower 20 cm of the bowel. When diagnosed, most nodules are no longer progressive…
article
2012
article
2012
ObjectiveTo establish an experimental model for the study of deep nodular endometriosis.DesignInduction of nodular endometriosis in baboons by grafting different uterine specimens to the peritoneal cavity.SettingResearch and university faci…
review
2012
Sampson's menstrual reflux theory is commonly used to explain the origin of endometriotic lesions in women. However, their pathogenesis remains largely unknown. Validated research models need to be developed with the aim of studying mechani…
review
2012
To define the role of surgery in the treatment of endometriomas, we review the literature available via PubMed and cross-reference the published data. We analyze the arguments in favor of and against surgical treatment of endometriomas and …
review
2011
INTRODUCTION: Current therapies for endometriosis cannot completely cure the disease, and patients present with high recurrence rates. Novel medical approaches are, therefore, needed. AREAS COVERED: In endometriosis, aromatase was long thou…
article
2011
ObjectiveTo evaluate the adverse effects of endometriomas on ovarian reserve.DesignAnalysis of prospectively collected biopsy samples.SettingGynecology research unit in a university hospital.Patient(s)Women younger than age 35 years with en…
article
2011
Endometriosis is one of the most frequently encountered benign diseases in gynecology. Complete resolution of endometriosis is not yet possible, but therapy has essentially three main objectives: (1) to preserve and improve fertility, (2) t…
article
2011
BACKGROUND: Steroid sulfatase (STS) is involved in estrogen biosynthesis and expressed in eutopic and ectopic endometrium of disease-free and endometriosis patients. The present study was designed to investigate its role in endometriosis de…
review
2011
Endometriosis is a chronic pelvic inflammatory process. Local inflammation is known to play a role in pain and infertility associated with the disease, and may be extensively involved in molecular and cellular processes leading to endometri…
article
2011
ObjectiveTo determinethe prevalence of spontaneous endometriosis andthe incidence of induced endometriosis after endocervical canal resection in baboons.DesignInduction and follow-up of endometriosis in baboons, which is one of the primate …
review
2011
Menometrorrhagia, defined as excessive and prolonged uterine bleeding occurring at irregular and/or frequent intervals, occurs in up to 24% of women aged 40-50 years. There are a wide range of causes of menometrorrhagia, although histologic…
review
2011
PURPOSE OF REVIEW: To evaluate different surgical options for the treatment of endometriomas. A heated debate is currently under way between advocates of excisional surgery and the ablative approach. With papers increasingly focusing on ova…
article
2011
Peritoneal endometriosis is a chronic inflammatory disease characterized by increased numbers of peritoneal macrophages and their secreted products. Inflammation plays a major role in pain and infertility associated with endometriosis, but …