Zhengyun Chen
No ORCID on file
· 22 papers in corpus
· active 2005-2026
Study types
- article 18
- other 2
- preprint 1
- review 1
Condition tags
- endometriosis 14
- adenomyosis 7
- infertility 6
- dysmenorrhea 4
- chronic_pelvic_pain 1
Top journals
Frequent coauthors
- Xin-Mei Zhang 15
- Chen Z 13
- Zhang X 8
- Yuanyuan Zhou 8
- Zhang Y 5
- Zhang L 5
- Li-Feng Zhang 5
- Cuicui Lin 4
- Lin J 4
- Xiaohang Yang 4
review
2026
BACKGROUND: Endometriosis is a prevalent estrogen-dependent inflammatory disorder that compromises women's quality of life and fertility through chronic pelvic pain, inflammation, and reproductive dysfunction. Current clinical management re…
other
2024
article
2024
Endometriosis seriously affects 6-10 % of reproductive women globally and poses significant clinical challenges. The process of ectopic endometrial cell colonization shares similarities with cancer, and a dysfunctional immune microenvironme…
article
2022
Diverticulum-like Adenomyosis on the Cesarean Scars of the Uterus: A Rare Type of Cystic Adenomyosis
A 43-year-old woman was admitted to the hospital with prolonged menstruation after cesarean delivery for 14 years and intermenstrual bleeding for half a year. Magnetic resonance imaging and ultrasonography revealed a mass of 3.3 cm in diame…
article
2022
article
2022
Although many studies show that patients with diffuse adenomyosis who underwent fertility-sparing surgery can have a successful pregnancy, their pregnancy outcomes are still controversial. The objective of this study was to determine long-t…
article
2021
BACKGROUND: Deep endometriosis (DE) is the most aggressive subtype of endometriosis. The diagnosis may be challenging, and no biomarkers that can discriminate women with DE from those without DE have been developed. AIM: To evaluate the rol…
article
2021
Endometriosis is an estrogen‐dependent chronic inflammatory disease that affects approximately 10% of women of reproductive age and up to 50% of women with infertility. The heterogeneity of the disease makes accurate diagnosis and treatment…
article
2021
INTRODUCTION: Endometriosis (EMs) is associated with severe chronic pelvic pain and infertility and the development of improved EMs treatment options is an ongoing focus. In this study, we investigated the effects of resveratrol on EMs and …
article
2020
BACKGROUND: A cystic lesion arising from the myometrium of the uterus, termed as cystic adenomyosis, has chocolate-like, thick viscous contents and contains various amounts of endometrial stroma below the glandular epithelium. It is an extr…
article
2020
The pathogenesis of endometriosis is not well understood at the moment, and the lack of effective biomarkers often leads to delayed diagnosis of the disease. Lipidomics provides a new approach for the diagnosis and prediction of endometrios…
preprint
2020
Abstract Background: Endometriosis is a complex disease in the field of gynecology that has certain limitations for its interim treatment. Resveratrol has been recently used for the treatment of endometriosis in experimental and clinical s…
article
2019
OBJECTIVE: To evaluate the efficacy and adverse effects of levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. METHODS: The clinical data of 75 patients with adenomyosis who had Mirena insertion in Women's…
article
2019
This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy.A total of 107 women who wished to conceive after sur…
article
2019
Drug therapy plays an important role in alleviating the symptoms related to adenomyosis, improving the curative effect of surgery, delaying the progress of disease and promoting assisted reproduction. Non-steroidal anti-inflammatory drugs (…
article
2019
Endometriosis (EMS) is a common gynecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. It is commonly associated with pelvic pain and infertility. The exact pathogenesis remains unclear and ma…
article
2019
OBJECTIVE: To determine the efficacy of second generation endometrial ablation (NovaSure) combined with levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. METHODS: Clinical data of patients with adenomyos…
article
2017
Brain-derived neurotrophic factor (BDNF) is a regulator for the formation and maintenance of chronic pain in various chronic disorders and has been shown to increase in the serum of women with endometriosis. However, BDNF expression in the …
article
2016
article
2005
[Determination of interleukine-16 levels in peritoneal fluid and serum of women with endometriosis].
OBJECTIVE: To investigate the role of interleukine-16 (IL-16) in the pathogenesis of endometriosis. METHODS: Enzyme-linked immunosorbent assay (ELISA) was used to determine the levels of IL-16 in peritoneal fluid and serum specimens of 22 w…
other
2005
article
2005
Interleukin-16 (IL-16) is a homotetramer of 14-kDa subunits discovered in 1982 as a T-cell-specific chemoattractant factor. The gene of IL-16 is located on chromosome 15 (15q26.1) and unrelated to other interleukins or chemokines (1). IL-16…