Kaihong Xu

No ORCID on file · 18 papers in corpus · active 2003-2024

Study types

  • article 15
  • other 3

Condition tags

  • endometriosis 17
  • dysmenorrhea 2
  • chronic_pelvic_pain 1
  • endometrioma 1
article 2024
Efficacy and Safety of Sanjie Analgesic Capsule in Patients with Endometriosis-Associated Pain: A Multicenter, 3:1 Randomized, Double-Blind, Placebo-Controlled Trial
Chinese journal of integrative medicine ·doi:10.1007/s11655-024-3756-y
article 2023
Identification of MKNK1 and TOP3A as ovarian endometriosis risk-associated genes using integrative genomic analyses and functional experiments
Computational and structural biotechnology journal ·doi:10.1016/j.csbj.2023.02.001

The risk of endometriosis (EM), which is a common complex gynaecological disease, is related to genetic predisposition. However, it is unclear how genetic variants confer the risk of EM. Here, via Sherlock integrative analysis, we combined …

article 2021
Sexual function in patients with endometriosis: a prospective case–control study in China
The Journal of international medical research ·doi:10.1177/03000605211004388

OBJECTIVE: Endometriosis is a common disease in women of childbearing age, leading to sexual dysfunction or loss of libido. We aimed to evaluated the effect of endometriosis on women's sexual function. METHODS: We performed a prospective ca…

article 2020
Elevated expressions of SHP2 and GAB2 correlated with VEGF in eutopic and ectopic endometrium of women with ovarian endometriosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2020.1787378

Aims: Protein tyrosine phosphatase Src-homology-2-domain-containing phosphatase 2 (SHP2) and adaptor protein Grb2-associated binding protein 2 (GAB2) can bind to each other in various signal transduction. However, the expression of SHP2 and…

other 2020
Epidermal growth factor promotes stromal cells migration and invasion via up-regulation of hyaluronate synthase 2 and hyaluronan in endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2020.05.005

OBJECTIVE: To investigate the role(s) of hyaluronan synthase 2 (HAS2) and hyaluronan in disease progression of endometriosis and epidermal growth factor (EGF)-induced motility changes of endometriotic cells. DESIGN: A case-control experime…

article 2020
Identification of key genes and pathways in endometriosis by integrated expression profiles analysis
PeerJ ·doi:10.7717/peerj.10171

The purpose of this study was to integrate the existing expression profile data on endometriosis (EM)-related tissues in order to identify the differentially expressed genes. In this study, three series of raw expression data were downloade…

other 2019
Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling
Scientific reports ·doi:10.1038/s41598-019-52741-1

Interleukin (IL)-34 plays a critical role in cell proliferation, differentiation, apoptosis, angiogenesis, inflammation and immunoregulation. Numerous diseases can be attributed to the dysregulation of IL-34 signaling. This study was perfor…

article 2019
CTHRC1 overexpression promotes ectopic endometrial stromal cell proliferation, migration and invasion via activation of the Wnt/β-catenin pathway
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2019.10.001
article 2018
Analysis of long non-coding RNA expression profiles using RNA sequencing in ovarian endometriosis
Gene ·doi:10.1016/j.gene.2018.06.046
article 2018
Massive vaginal hemorrhage caused by cervical endometriosis
Taiwanese journal of obstetrics & gynecology ·doi:10.1016/j.tjog.2018.10.026
other 2018
Upregulation of S100A6 in patients with endometriosis and its role in ectopic endometrial stromal cells
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2018.1451506

S100 calcium-binding protein A6 (S100A6) is up-regulated in many malignancies and overexpression of S100A6 has been identified associated with proliferation, migration and invasion phenotype in several cancer cells. In the present study, we…

article 2017
Correlation of polypeptide N-acetylgalactosamine transferases-3 and -6 to different stages of endometriosis
Archives of gynecology and obstetrics ·doi:10.1007/s00404-017-4344-6
article 2016
Silencing of SRA1 Regulates ER Expression and Attenuates the Growth of Stromal Cells in Ovarian Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116670036
article 2015
[AQP5 gene silencing inhibits proliferation and migration of ectopic endometrial glandular epithelial cells in endometriosis].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2015.05.08

OBJECTIVE: To investigate the effect of aquaporin 5(AQP5) on proliferation and migration of ectopic endometrial epithelial cells. METHODS: AQP5 shRNA interference fragments were designed and transfected into ectopic endometrial epithelial c…

article 2014
Increased steroid receptor RNA activator protein (SRAP) accompanied by decreased estrogen receptor-beta (ER-β) levels during the malignant transformation of endometriosis associated ovarian clear cell carcinoma
Acta histochemica ·doi:10.1016/j.acthis.2014.02.007
article 2010
Phosphatase of regenerating liver-3: a novel and promising marker in human endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.10.065
article 2009
Immunohistochemical detection of aquaporin expression in eutopic and ectopic endometria from women with endometriomas
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.08.053
article 2003
Glutathione S-transferase M1 and T1 genotypes and endometriosis risk: a case-controlled study.
Chinese medical journal

OBJECTIVE: To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). METHODS: Polymerase chain reaction (PCR) technique was used to detect the presence or absence of the GSTM1 an…