Hu Q

Abstract Objective This study aims to systematically compare the short-term efficacy and safety differences between daily oral 2 mg Dienogest (DNG) and daily oral 10 mg Mifepristone (MIF) in the treatment of patients with symptomatic aden…

Sleep deprivation (SD) is a significant risk factor for reproductive dysfunction. This review aims to synthesize evidence establishing that oxidative stress (OS) is the key pathological mediator of SD-induced reproductive impairments in bot…

BackgroundCotton phenol is a yellowish-brown polyphenol hydroxybinaphthyl aldehyde compound mainly found in the roots, stems, leaves and seeds of cotton; a plant of the mallow family that has been widely used in the study of antifertility a…

Study questionDo novel per- and poly-fluoroalkyl substances (Novel PFAS) have associations with premature ovarian insufficiency (POI)?Summary answerHexafluoropropylene oxide dimer acid (HFPO-DA), perfluorobutanoic acid (PFBA), perfluoropent…

BackgroundFallopian tube carcinoma is one of the most malignant gynecological tumors, with its exact etiology remaining largely unclear. Genetic factors contribute to ~20% of ovarian, fallopian tube, and peritoneal cancers, and gene polymor…

PURPOSE: This study aimed to compare the clinical pregnancy rates of hysterosalpingography (HSG) with water-based contrast and hysterosalpingo-contrast sonography (HyCoSy) to investigate their impact on fertility outcomes in women with endo…

BackgroundPurinergic P2 receptors, which can be divided into ionotropic P2X receptors and metabotropic P2Y receptors, mediate cellular signal transduction of purine or pyrimidine nucleoside triphosphates and diphosphate. Based on the wide e…

BACKGROUND: Female infertility is a global health issue, with metabolic disorders emerging as significant contributors. Liver steatosis, characterized by excessive hepatic fat accumulation, is closely linked to metabolic dysfunction and may…

BackgroundAppendicitis is an abdominal medical emergency and can be of various types. It can lead to a series of gastrointestinal symptoms and can affect health status. Therefore, attention should be paid to the diagnosis of appendicitis to…

Previous research has indicated that Polyphyllin I (PPI) possesses potent anticancer properties. However, its impact on endometriosis remains unexplored. This study aims to investigate the inhibitory effects of PPI on ectopic endometrial st…

BACKGROUND: Endometriosis (EMs) and adenomyosis (AD) are prevalent gynecological disorders with overlapping symptoms but potentially distinct pathophysiology. This study was to understand different gene expression patterns of eutopic endome…

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of…

Despite several factors influencing reproduction in geese, but the precise molecular mechanisms of egg cessation are not fully understood. In the present study, the hematopoietic parameters and serum hormone levels in Wanxi white geese were…

QiuXia Hu,1,* Yi Yao,2,* XiaoHui Xie,1 XiaoMei Zhong,1 Yong Luo,1 Xiaoqin Huang1 1Department of Gynecology, The First People’s Hospital of Neijiang, Sichuan, 641000, People’s Republic of China; 2Department of Cardiothoracic Surgery,…

BACKGROUND: The levonorgestrel-releasing intrauterine system (LNG-IUS) is now widely used for the treatment of heavy menstrual bleeding and endometrial hyperplasia, and its clinical application has been extended to adenomyosis. By releasing…

This report described three cases with long-term severe dysmenorrhea, and these cases were referred to our department for medical help. The diagnosis of accessory cavitated uterine malformation (ACUM) was considered based on symptoms and ul…

Endometriosis is a multifactorial disease associated with inflammation. Vitamin D has anti-inflammatory, antiproliferative, anti-oxidative, and immunomodulatory effects. Whether vitamin D levels are correlated with endometriosis is a subjec…

BackgroundExposure to metal could impact women's depression risk. However, the connection and mechanisms between metalloestrogens exposure and depression are still not fully understood. We aim to explore the associations between metalloestr…

BACKGROUND: Previous studies have suggested that oil-based contrast agents used during hysterosalpingography (HSG) in infertile patients can enhance fertility. However, limited research has investigated the effect of oil-based contrast medi…

Given the high concentration of iron in the micro-environment of ovarian endometriosis, it is plausible to hypothesize that ectopic endometrial cells may be more susceptible to undergoing ferroptosis. Manipulation of ferroptosis has been ex…

ObjectiveThe sequelae of pelvic inflammatory disease (SPID) are major causes of secondary infertility. Modified Hongteng Baijiang decoction (MHTBD) has produced positive results in the treatment of patients with chronic pelvic inflammatory …

BACKGROUND: Thyroid autoimmunity (TAI) is associated with infertility and complications during pregnancy. However, the prevalence of thyroid autoantibodies in women with infertility remains unclear due to variability in study designs, sampl…

IntroductionInfertility affects 8-12% of couples worldwide, with 15-30% classified as unexplained infertility (UI). Thyroid autoimmunity (TAI), the most common autoimmune disorder in women of reproductive age, may impact fertility and pregn…

This study reports the outcomes of an innovative fertility-preserving surgery for the treatment of diffuse adenomyosis that is known as a surgery for protection of uterine structure for healing (PUSH Surgery). Developed at Peking University…