Endoscopic Submucosal Dissection for the Treatment of Rectal Endometriosis in Postmenopausal Women

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This study investigated the efficacy and safety of endoscopic submucosal dissection (ESD) for treating rectal endometriosis in postmenopausal women.

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This case report describes the successful application of endoscopic submucosal dissection (ESD) to treat rectal endometriosis in a postmenopausal woman, a demographic where such deep infiltrating lesions are less common. The authors detail the procedural steps and outcomes, highlighting ESD as a viable minimally invasive option for managing gastrointestinal involvement of endometriosis when surgical resection is not immediately required. The paper explicitly focuses on this specific clinical presentation, demonstrating that ESD can effectively remove rectal endometrial implants without the need for more extensive bowel surgery. This paper is centrally about endometriosis — specifically the management of deep infiltrating endometriosis affecting the rectum in a postmenopausal patient.

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Data Availability No datasets were generated or analysed during the current study. References Bazot M, Kermarrec E, Bendifallah S, Daraï E. MRI of intestinal endometriosis. Best Pract Res Clin Obstet Gynaecol 2021;71:51–63. https://doi.org/10.1016/j.bpobgyn.2020.05.013. Bazot M, Detchev R, Cortez A et al. Transvaginal sonography and rectal endoscopic sonography for the assessment of pelvic endometriosis: a preliminary comparison. Hum Reprod 2003;18:1686–1692. https://doi.org/10.1093/humrep/deg314. Arakawa T, Fukuda S, Hirata T et al. PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis. Reprod Sci 2020;27:1580–1586. https://doi.org/10.1007/s43032-020-00186-7. Funding This research did not receive any specific grant. Author information Authors and Affiliations Contributions HZ contributed to manuscript writing and editing. QH contributed to data collection. HS and MX contributed to the conception and final revision of the paper. All authors reviewed and approved the final manuscript. Corresponding author Ethics declarations Conflict of interest The authors declare no competing interests. Informed consent Written informed consent was obtained from the patient for publication of this report and any accompanying images. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Zhu, H., Hu, Q., Xiong, M. et al. Endoscopic Submucosal Dissection for the Treatment of Rectal Endometriosis in Postmenopausal Women. Dig Dis Sci (2026). https://doi.org/10.1007/s10620-026-09680-5 Received: Accepted: Published: Version of record: DOI: https://doi.org/10.1007/s10620-026-09680-5

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endometriosis

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