Luke B

BackgroundFertility preservation (FP) may be underused after cancer diagnosis because of uncertainty around delays to cancer treatment and subsequent reproductive success.MethodsWomen aged 15 to 39 years diagnosed with cancer between 2004 a…

PurposeTo generate a large cohort of children born after assisted reproductive technology (ART) in the UK between 1992 and 2009, their naturally conceived siblings (NCS) and matched naturally conceived population (NCP) controls and linking …

Study questionWhat is the association between ART conception and treatment parameters and the risk of birth defects?Summary answerCompared to naturally conceived singleton infants, the risk of a major nonchromosomal defect among ART singlet…

BackgroundAlthough in vitro fertilization has been associated with an increased risk for hypertensive disorders of pregnancy, the association of risk with in vitro fertilization treatment parameters is unclear.ObjectiveTo evaluate risk for …

ImportanceIn vitro fertilization (IVF) is associated with birth defects and imprinting disorders. Because these conditions are associated with an increased risk of childhood cancer, many of which originate in utero, descriptions of cancers …

PurposeTo evaluate factors associated with interpregnancy interval (IPI) among women treated with in vitro fertilization (IVF).MethodsWomen with at least two cycles of IVF between 2004 and 2013 were identified from the SART CORS database an…

BackgroundIt is unknown whether the risk of adverse outcomes in twin pregnancies among subfertile women, conceived with and without in vitro fertilization, differs from those conceived spontaneously.ObjectiveWe sought to evaluate the effect…

PurposeThe aim of this study is to evaluate frequency of hospitalization before, during, and after assisted reproductive technology (ART) treatment by cycle outcome.MethodsSix thousand and one hundred thirty women residing in Massachusetts …

Infertility, defined as the inability to conceive within 1 year of unprotected intercourse, affects an estimated 80 million individuals worldwide, or 10-15% of couples of reproductive age. Assisted reproductive technology includes all infer…

BackgroundBirths to subfertile women, with and without infertility treatment, have been reported to have lower birthweights and shorter gestations, even when limited to singletons. It is unknown whether these decrements are due to parental …

Study questionHow do the assisted reproductive technology (ART) outcomes of women presenting for ART after cancer diagnosis compare to women without cancer?Summary answerThe likelihood of a live birth after ART among women with prior cancer…

ObjectiveTo evaluate pregnancy and birth outcomes by type of infertility treatment received.Study designAssisted reproductive technology (ART) data on women who were both treated and gave birth in Massachusetts were linked to vital records …

ObjectiveTo assess whether risk of severe maternal morbidity at delivery differed for women who conceived using assisted reproductive technology (ART), those with indicators of subfertility but no ART ("subfertile"), and those who had neith…

OBJECTIVE: To compare the risks for adverse pregnancy and birth outcomes by diagnoses with and without assisted reproductive technology (ART) treatment to non-ART pregnancies in fertile women. DESIGN: Historical cohort of Massachusetts vit…

ObjectiveTo evaluate risks for adverse pregnancy outcomes by number of embryos transferred (ET) and fetal heartbeats (FHB) in assisted reproductive technology-conceived singleton live births.DesignLongitudinal cohort using cycles reported t…

ObjectiveThe purpose of this study was to use a validated prediction model to examine whether single embryo transfer (SET) over 2 cycles results in live birth rates (LBR) comparable with 2 embryos transferred (DET) in 1 cycle and reduces th…

OBJECTIVE: To evaluate assisted reproductive technology (ART) pregnancy outcomes by infertility diagnosis. STUDY DESIGN: ART data on women who were treated and gave birth in Massachusetts were linked to vital records and hospital utilizati…

ObjectiveTo evaluate the risk of cancer after assisted reproductive technology (ART) therapy.DesignLongitudinal cohort study.SettingNot applicable.Patient(s)New York, Texas, and Illinois residents between 2004 and 2009, treated with ART, co…

OBJECTIVE: To evaluate the correlation between total gonadotropin dose and live birth rate. DESIGN: Retrospective analysis. SETTING: Not applicable. PATIENT(S): A total of 658,519 fresh autologous cycles of in vitro fertilization (IVF) r…

ObjectiveTo compare on a population basis the birth outcomes of women treated with assisted reproductive technologies (ART), women with indicators of subfertility but without ART, and fertile women.DesignLongitudinal cohort study.SettingNot…

ObjectiveTo develop a model predictive of live-birth rates (LBR) and multiple birth rates (MBR) for an individual considering assisted reproduction technology (ART) using linked cycles from Society for Assisted Reproductive Technology Clini…

ObjectiveTo identify a group of deliveries to mothers with indicators of subfertility (SUBFERTILITY).DesignLongitudinal cohort study.SettingHospital.Patient(s)A total of 334,152 deliveries to Massachusetts mothers in a Massachusetts hospita…

PurposeTo compare ages of mothers and of fathers at delivery in couples who are fertile, subfertile, and subfertile treated with assisted reproductive technology (ART) and to characterize birth outcomes in the ART population according to pa…

ObjectiveTo model morphological assessments of embryo quality that are predictive of live birth.DesignLongitudinal cohort using cycles reported in the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System (SART CORS)…

PURPOSE: This study uses linked cycles of assisted reproductive technology (ART) to examine cumulative live birth rates, birthweight, and length of gestation by diagnostic category. METHODS: We studied 145,660 women with 235,985 ART cycles…