Hanyaloglu AC

No ORCID on file · 5 papers in corpus · active 2020-2024

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2024
Journal of molecular endocrinology ·doi:10.1530/JME-23-0153

The prostanoid G protein-coupled receptor (GPCR) EP2 is widely expressed and implicated in endometriosis, osteoporosis, obesity, pre-term labour and cancer. Internalisation and intracellular trafficking are critical for shaping GPCR activit…

2022
Scientific reports ·doi:10.1038/s41598-022-12495-9

The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled receptor activated by both human chorionic gonadotropin (hCG) and luteinizing hormone (LH), two structurally related gonadotropins with essential roles…

2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.798866

Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and complex pathways. Classically, FSHR activates Gαs to increase intracellular levels …

2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab065

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) play complementary roles in follicle development and ovulation via a complex interaction in the hypothalamus, anterior pituitary gland, reproductive organs, and oocytes. Impair…

2020
iScience ·doi:10.1016/j.isci.2020.101812

Classically, follicle-stimulating hormone receptor (FSHR)-driven cAMP-mediated signaling boosts human ovarian follicle growth and oocyte maturation. However, contradicting in vitro data suggest a different view on physiological significance…