Brighton PJ

No ORCID on file · 3 papers in corpus · active 2015-2022
2022
Expression and function of the luteinizing hormone choriogonadotropin receptor in human endometrial stromal cells.
Scientific reports ·doi:10.1038/s41598-022-12495-9

The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled receptor activated by both human chorionic gonadotropin (hCG) and luteinizing hormone (LH), two structurally related gonadotropins with essential roles…

2016
Progesterone-Dependent Induction of Phospholipase C-Related Catalytically Inactive Protein 1 (PRIP-1) in Decidualizing Human Endometrial Stromal Cells.
Endocrinology ·doi:10.1210/en.2015-1914

Decidualization denotes the transformation of endometrial stromal cells into specialized decidual cells. In pregnancy, decidual cells form a protective matrix around the implanting embryo, enabling coordinated trophoblast invasion and forma…

2015
The clock protein period 2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.14-267195

Implantation requires coordinated interactions between the conceptus and surrounding decidual cells, but the involvement of clock genes in this process is incompletely understood. Circadian oscillations are predicated on transcriptional-tra…