Jan J. Brosens

ORCID: 0000-0003-0116-9329 · 67 papers in corpus · active 1993-2023

Study types

  • article 29
  • review 19
  • preprint 8
  • book-chapter 5
  • other 3

Condition tags

  • endometriosis 35
  • mesh:D004715 27
  • infertility 10
  • adenomyosis 8
  • mesh:D004412 2
  • dysmenorrhea 2
  • endometrioma 1
  • chronic_pelvic_pain 1
  • mesh:D017699 1
preprint 2023
·doi:10.1158/0008-5472.c.6500271.v1

AbstractEndometrial cancer is the most common malignancy of the lower female reproductive tract. The tumor suppressor FOXO1 is downregulated in endometrial cancer compared with normal endometrium but the underlying mechanisms are not well u…

preprint 2023
·doi:10.1158/0008-5472.22382649.v1

Supplementary Figure 1 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2023
·doi:10.1158/0008-5472.22382649

Supplementary Figure 1 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2023
·doi:10.1158/0008-5472.22382646.v1

Supplementary Figure 2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2023
·doi:10.1158/0008-5472.22382646

Supplementary Figure 2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2023
·doi:10.1158/0008-5472.22382643.v1

Supplementary Figure Legends 1-2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2023
·doi:10.1158/0008-5472.22382643

Supplementary Figure Legends 1-2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer

preprint 2022
·doi:10.1101/2022.05.27.493373

ABSTRACT Women with endometriosis have a profound association with autoimmunity. An excess of autoantigens in the peritoneal cavity resulting from retrograde menstruation could lead to inflammation and pathologic autoimmunity. Using a nativ…

article 2017
Nature cell biology ·doi:10.1038/ncb3516
letter 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.10.010
review 2016
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians ·doi:10.1080/14767058.2016.1216540

Neonatal uterine bleeding (NUB) occurs in approximately 5% of newborns and is generally considered to be of little clinical significance. However, the real clinical importance of this condition and its long-term implications remain to be de…

review 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116637919
article 2015
·doi:10.1016/j.ultrasmedbio.2015.06.002
article 2015
·doi:10.5301/je.5000218

Background Different fetomaternal conditions may influence the risk of endometriosis during adolescence and in adult life; here we focus on the hormonal maturation of the fetal endometrium in the final stages of pregnancy and on the theory …

article 2015
review 2015
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians ·doi:10.3109/14767058.2015.1040756

BACKGROUND: Scientific data on the phenomenon of uterine bleeding in the neonate (NUB) began to appear over a century ago when angiogenesis and petechial haemorrhages in the endometrium of newborn female infants, as well as fluid blood with…

review 2014
Molecular human reproduction ·doi:10.1093/molehr/gau025

The pathogenesis of early-onset endometriosis has recently been revisited, sparked by the discovery of endometrial stem/progenitor cells and their possible role in endometriosis, and because maternal pregnancy hormone withdrawal following d…

article 2013
Medical molecular morphology ·doi:10.1007/s00795-013-0059-3
article 2013
·doi:10.1093/humrep/det211

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

review 2013
Human reproduction update ·doi:10.1093/humupd/dmt025

BACKGROUND Mechanisms underlying early reproductive loss in the human are beginning to be elucidated. The migratory and invasive capacity of human endometrial stromal cells (ESCs) is increasingly recognized to contribute to the intense tiss…

article 2012
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2012.01845.x

AIM: The rate of oocyte decline follows a biphasic pattern, characterized by acceleration between 32 and 38 years old. Ovarian reserve is also affected by external factors, including ovarian disease and iatrogenic damage. The aim of this st…

review 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.02.024
review 2012
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2012.01.022

The eutopic endometrium in women suffering from endometriosis is different in many ways from that of healthy controls. Both proliferative and secretory eutopic endometria exhibit changes in endometriosis with heterogeneous responses. In add…

editorial 2012
·doi:10.1016/j.mce.2012.02.023
other 2011
Current drug targets ·doi:10.2174/138945011796150253

All fundamental reproductive events in the human ovary and uterus, including ovulation, implantation and menstruation, are dependent upon profound tissue remodelling, characterized by cyclical waves of cell proliferation, differentiation, r…