Thomas D’Hooghe

No ORCID on file · 252 papers in corpus · active 1991-2026

Study types

  • article 182
  • review 34
  • letter 11
  • book-chapter 8
  • other 6

Condition tags

  • endometriosis 225
  • mesh:D004715 133
  • infertility 36
  • dysmenorrhea 8
  • chronic_pelvic_pain 5
  • dyspareunia 5
  • mesh:D017699 3
  • adenomyosis 3
  • endometrioma 2
  • die_deep_infiltrating 2
other 2026
Human reproduction open ·doi:10.1093/hropen/hoag031
review 2024
·doi:10.37766/inplasy2024.1.0066

Any ASRM stage [19] of en-dometriosis, any menstrual stage and any technique for miRNA expression analysis were allowed. Participant or population Patients with endometriosis.Intervention Assesment of circulating biomarkers.Comparator Asymp…

article 2024
Biomedicines ·doi:10.3390/biomedicines12040888

The aim of this systematic review is to assess the power of circulating miRNAs as biomarkers as a diagnostic tool in endometriosis. In endometriosis-suspected women with uncertain imaging, the only way to confirm or exclude endometriosis wi…

preprint 2024
·doi:10.1101/2024.03.28.583957

ABSTRACT Background Endometriosis is a complex disease, and its pathophysiology is still unclear. Therefore, endometriosis animal models need to be carefully selected and examined to be useful for identification of novel therapies for women…

other 2023
Human reproduction update ·doi:10.1093/humupd/dmac040

BACKGROUND: Several GnRH antagonist protocols are currently used during COS in the context of ART treatments; however, questions remain regarding whether these protocols are comparable in terms of efficacy and safety. OBJECTIVE AND RATIONA…

other 2022
Human Reproduction ·doi:10.1093/humrep/deac134
review 2021
Human Reproduction ·doi:10.1093/humrep/deab254

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal associat…

article 2021
·doi:10.1093/humrep/deab130.329

Abstract Study question Is endometriosis related to worse outcome of assisted reproductive techniques (ART)? Summary answer Cumulative incidence of live birth in patients with and without endometriosis at laparoscopy was similar, although d…

article 2021
Human Reproduction ·doi:10.1093/humrep/deab163

STUDY QUESTION: Does ultra-long downregulation with a GnRH agonist (triptorelin depot) in previously operated patients with endometriosis improve the rate of clinical pregnancy with positive fetal heart beat (CPHB) in the subsequent initiat…

erratum 2020
Reproductive biology ·doi:10.1016/j.repbio.2020.08.005
book-chapter 2020
·doi:10.1093/med/9780198766360.003.0045

Endometriosis is a chronic oestrogen-dependent gynaecological disease present in approximately 10% of women of reproductive age and up to 30–50% of women with infertility and/or pain. It is defined as the presence of endometrial-like tissue…

article 2020
Human Reproduction ·doi:10.1093/humrep/deaa346

STUDY QUESTION: Can the Endometriosis Fertility Index (EFI) be estimated accurately before surgery? SUMMARY ANSWER: The EFI can be estimated accurately based on mere clinical/ultrasound information, with some improvement after adding data f…

article 2020
Human genetics ·doi:10.1007/s00439-020-02223-6
letter 2020
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.12.031
article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00081-w
article 2019
Human Reproduction ·doi:10.1093/humrep/dez028

STUDY QUESTION: Does the GnRH antagonist, ASP1707, reduce endometriosis-associated pelvic pain? SUMMARY ANSWER: ASP1707 significantly reduced endometriosis-associated pelvic pain in a dose-related manner. WHAT IS KNOWN ALREADY: GnRH agonist…

review 2019
Biology of reproduction ·doi:10.1093/biolre/ioz016

Endometriosis is an important gynecological disease, affecting 10% of reproductive age women, and associated with pain, infertility, reduced quality of life, and high health economic cost. Except for ultrasound detection of ovarian endometr…

article 2019
Gynecologic and obstetric investigation ·doi:10.1159/000500626

BACKGROUND: Endometriosis is a common disorder that affects 6-10% of reproductive age women. In a previous study, we demonstrated that a polymorphism in let-7 microRNA-binding site in the 3' untranslated region of the KRAS gene was found in…

article 2019
Human Reproduction ·doi:10.1093/humrep/dez116

STUDY QUESTION: Can plasma miRNAs be used for the non-invasive diagnosis of endometriosis in infertile women? SUMMARY ANSWER: miRNA-based diagnostic models for endometriosis failed the test of independent validation. WHAT IS KNOWN ALREADY: …

article 2019
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.08.082

Object:\nTo assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity.\n\nDesign:\nMulticentre cross-sectional study with prospective recruitment.\n\nSetting:\nSixteen clinical centers in ten countri…

article 2019
BJOG: An International Journal of Obstetrics & Gynaecology ·doi:10.1111/1471-0528.15880

OBJECTIVE: To evaluate the reproducibility of the Endometriosis Fertility Index (EFI). DESIGN: Single-cohort prospective observational study. SETTING: University hospital. POPULATION: Women undergoing laparoscopic resection of any rASRM-sta…

article 2019
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.21868

OBJECTIVE: To compare the value of using one-stop magnetic resonance imaging (MRI) vs standard radiological imaging as a supplement to transvaginal ultrasonography (TVS) for the preoperative assessment of patients with endometriosis referre…

article 2019
BioMed research international ·doi:10.1155/2019/3673060

There is a great need for a noninvasive diagnosis for endometriosis. Several biomarkers and biomarker panels have been proposed. Biomarker models consisting of CA-125, VEGF, Annexin V, and glycodelin/sICAM-1 were previously developed by our…

review 2019
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2019.06.006
article 2018
·doi:10.1177/2284026518784236

Background: Clinical management of endometriomas, prior to starting treatment with assisted reproductive technologies (ART), has since long been a matter of debate. Whereas cystectomy has been advocated in the past, recently more evidence h…