M. Breckwoldt

Cytokines are important regulators of reproductive functions. Significant amounts of interleukin-6 (IL-6) have been detected in the serum and ascites of patients with ovarian hyperstimulation syndrome (OHSS). These findings suggest the invo…

In 193 patients with fibrocystic breast diseases in 46% basal prolactin levels were elevated and many women had an increased reaction to TRH test with increased TSH and PRL serum levels. The author recommend for treatment progestogens dopam…

The ovarian function of 11 patients suffering from estrogen-dependent disorders and ovarian dysfunction was suppressed by monthly administrations of an analogue of luteinizing hormone-releasing hormone (LH-RH). During the initial 11 to 18 d…

Primary dysmenorrhea occurs mostly in young women with a painful bleeding pattern. In a recent study, 72% of 19-year-old women had light, 19% had medium to severe, and 8% had severe symptoms. Secondary dysmenorrhea means pathological organi…

Six patients suffering from endometriosis (Acosta stages I to III) were treated by luteinizing hormone-releasing hormone agonists (LHRH-A). In 3 of the 6 patients buserelin (Hoechst AG, FRG) was subcutaneously infused using an osmotic minip…

The widening effect of Sulproston 500 microgram IM on the cervix uteri was investigated in a double-blind study conducted in 50 non-pregnant volunteers. In women in the postmenopausal stage who had been given Sulproston, resistance-free wid…

Clinical findings suggest a relationship between prostaglandins of the F2a group progesterone and dysmenorrhea. The menstrual flow of 5 dysmenorrhoic women aged 20-30 years was collected 2 cycles with and 2 cycles without local intrauterine…

The paper reports on intravenous and intrauterine application of Prostaglandin F2alpha and its 15-methyl derivative for the treatment of severe uterine bleedings in obsteterics and gynaecology. The effectiveness of the compounds is demonstr…